PATJ 抗体 (AA 1001-1200) (HRP)
Quick Overview for PATJ 抗体 (AA 1001-1200) (HRP) (ABIN1413302)
抗原
See all PATJ (INADL) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1001-1200
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预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human PATJ
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亚型
- IgG
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应用备注
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IHC-P 1:200-400
IHC-F 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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注意事项
- Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- PATJ (INADL) (InaD-Like (INADL))
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别名
- PATJ
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背景
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Synonyms: Channel interacting PDZ domain protein, Cipp, FLJ26982, hINADL, Inactivation no after potential D like protein, INAD like, InaD like Drosophila, INAD like protein, INADL, INADL protein, PALS 1 associated tight junction protein, PALS1 associated tight junction protein, PATJ, PDZ domain protein, PDZ domain protein Drosophila inaD like, Post synaptic density 95 / discs large / zonula occludens 1 domain protein, Protein associated to tight junctions, INADL_HUMAN .
Background: The membranes of myelinating Schwann cells are joined by tight, gap and adherens junctions, all of which are found in regions of noncompact myelin: the paranodal loops, incisures of Schmidt-Lanterman and mesaxons. Tight junctions help establish polarity in mammalian epithelia by forming a physical barrier that separates apical and basolateral membranes. Pals-associated tight junction protein (PATJ), the human homolog of Drosophila Discs Lost, is differentially localized in myelinating Schwann cells. PATJ associates with Claudin-1, CRB1 (a transmembrane protein that plays a role in epithelial cell polarity and photoreceptor development), and Pals1 (a Lin-7 associated protein). The PATJ/Pals1/CRB1 complex can form a tripartite tight junction in epithelial cells crucial to their integrity.
抗原
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