SHROOM2 抗体 (AA 701-850) (Cy5)
Quick Overview for SHROOM2 抗体 (AA 701-850) (Cy5) (ABIN1413232)
抗原
See all SHROOM2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 701-850
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预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human APXL
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亚型
- IgG
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anti-Shroom Family Member 2 (SHROOM2) (C-Term) antibody
SHROOM2 适用: 人 WB, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Shroom Family Member 2 (SHROOM2) (AA 213-405) antibodySHROOM2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Shroom Family Member 2 (SHROOM2) (AA 1295-1344) antibodySHROOM2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 小鸡, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Shroom Family Member 2 (SHROOM2) (C-Term) antibodyVerified SHROOM2 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Shroom Family Member 2 (SHROOM2) (Middle Region) antibodySHROOM2 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- SHROOM2 (Shroom Family Member 2 (SHROOM2))
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别名
- APXL
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背景
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Synonyms: Apical like protein, Apical like protein APXL protein, apical protein of Xenopus-like, Apical protein Xenopus laevis like, apical protein, Xenopus laevis-like, apical protein-like, apical protein-like Xenopus laevis, Apical-like protein, APX homolog of Xenopus, C630003H05Rik, DKFZp781J074, FLJ39277, HSAPXL, Liver regeneration-related protein LRRG167, Protein Apxl, Protein Shroom2, Shrm2, SHRM2_HUMAN, SHROOM 2, Shroom family member 2, shroom2.
Background: APXL is a 1,616 amino acid protein that localizes to a variety of locations within the cell, including the cytoplasm, the cytoskeleton, the cell junction and the apical cell membrane. Containing one ASD1 domain, one ASD2 domain and one PDZ domain, APXL interacts with F-Actin and is thought to mediate endothelial cell morphology during cell spreading, possibly regulating melanosome biogenesis and inducing _ Tubulin redistribution. APXL is expressed in kidney, brain, lung, pancreas and placenta and is overexpressed in melanomas, suggesting a role in tumor transformation and metastasis. The gene encoding APXL maps to human chromosome X, which contains nearly 153 million base pairs and houses over 1,000 genes. In conjunction with chromosome Y, chromosome X is responsible for sex determination. There are a number of conditions related to an abnormal number and combination of sex chromosomes, some of which include Turner's syndrome, color blindness, hemophilia and Duchenne muscular dystrophy.
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途径
- Cell-Cell Junction Organization, Asymmetric Protein Localization
抗原
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