PHYHIP 抗体 (AA 231-330) (Cy5)
Quick Overview for PHYHIP 抗体 (AA 231-330) (Cy5) (ABIN1412026)
抗原
See all PHYHIP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 231-330
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预测反应
- Human,Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human PHYHIP
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亚型
- IgG
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anti-Phytanoyl-CoA 2-Hydroxylase Interacting Protein (PHYHIP) (AA 101-150) antibody
PHYHIP 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, Bat, Hamster, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Phytanoyl-CoA 2-Hydroxylase Interacting Protein (PHYHIP) (AA 51-100) antibodyPHYHIP 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 斑马鱼, Bat, Hamster, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Phytanoyl-CoA 2-Hydroxylase Interacting Protein (PHYHIP) (N-Term) antibodyPHYHIP 适用: 人, 小鼠, 大鼠, 犬 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- PHYHIP (Phytanoyl-CoA 2-Hydroxylase Interacting Protein (PHYHIP))
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别名
- PHYHIP
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背景
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Synonyms: DYRK1A interacting protein 3, DYRK1AP3, PAHX AP1, PAHXAP1, phytanoyl CoA 2 hydroxylase interacting protein, phytanoyl CoA alpha hydroxylase associated protein, Phytanoyl CoA hydroxylase associated protein 1, Phytanoyl CoA hydroxylase interacting protein, Similar to a putative C.elegans gene encoded in cosmid M01B2, PHYIP_HUMAN.
Background: PHYHIP (Phytanoyl-CoA hydroxylase-interacting protein) is a 330 amino acid protein that is strongly expressed in brain, with weak expression in ovary, small intestine and ovary. In transgenic mice, overexpression of PHYHIP in heart results in tachycardia and tachyarrhythmia. PHYHIP interacts with the Refsum disease gene product, PAHX, indicating that PHYHIP may play a role in the CNS deficits of Refsum disease, which is characterized by cerebellar degeneration, neurologic damage and peripheral neuropathies. PHYHIP also interacts with Dyrk1A, a protein that that is overexpressed in brain of Down-syndrome patients, therefore PHYHIP may participate in some of the neurological abnormalities of Down syndrome. Significantly, the gene encoding PHYHIP is localized to a region of the short arm of human chromosome 8 that is frequently found deleted in prostate, breast and several other types of cancers.
抗原
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