NETO2 抗体 (AA 151-250) (Cy7)
Quick Overview for NETO2 抗体 (AA 151-250) (Cy7) (ABIN1411860)
抗原
See all NETO2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 151-250
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预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human NETO2
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亚型
- IgG
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- NETO2 (Neuropilin (NRP) and Tolloid (TLL)-Like 2 (NETO2))
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别名
- NETO2
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背景
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Synonyms: Brain specic transmembrane protein, Brain specic transmembrane protein containing 2 CUB and 1 LDL receptor class A domains protein 2, Brain-specic transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2, BTCL2, FLJ10430, FLJ14724, FLJ90456, NEOT2, NETO 2, Neto2, NETO2_HUMAN, Neuropilin NRP and tolloid TLL like 2, Neuropilin and tolloid like protein 2, Neuropilin and tolloid-like protein 2.
Background: NETO2 is a 525 amino acid single-pass type I membrane protein that contains two CUB domains and one LDL-receptor class A domain. Expressed as multiple alternatively spliced isoforms, NETO2 is thought to play a role in the development and maintenance of neuronal circuitry, possibly playing a role in proper brain function. The gene encoding NETO2 maps to human chromosome 16, which is associated with a variety of genetic disorders, encodes over 900 genes and comprises nearly 3 % of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.
抗原
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