KALRN 抗体 (AA 1401-1500) (HRP)
Quick Overview for KALRN 抗体 (AA 1401-1500) (HRP) (ABIN1411652)
抗原
See all KALRN 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1401-1500
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预测反应
- Human,Mouse,Rat,Dog,Pig,Horse,Chicken
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human KALRN/Duo
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亚型
- IgG
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anti-Kalirin, RhoGEF Kinase (KALRN) (C-Term) antibody
Verified KALRN 适用: 人 ELISA, IHC, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Kalirin, RhoGEF Kinase (KALRN) (C-Term) antibodyKALRN 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Kalirin, RhoGEF Kinase (KALRN) (AA 2410-2661) antibodyKALRN 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Kalirin, RhoGEF Kinase (KALRN) (Internal Region) antibodyKALRN 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Kalirin, RhoGEF Kinase (KALRN) (Center) antibodyKALRN 适用: 人, 小鼠, 大鼠, 猴 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
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IHC-P 1:200-400
IHC-F 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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注意事项
- Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- KALRN (Kalirin, RhoGEF Kinase (KALRN))
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别名
- KALRN/Duo
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背景
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Synonyms: Duo, FLJ16443, HAPIP, Huntingtin associated protein interacting protein duo , Huntingtin-associated protein-interacting protein, Kalirin isoform 2, Kalirin, KALRN , KALRN_HUMAN , Protein Duo, RhoGEF kinase, Serine/threonine kinase with Dbl and pleckstrin homology domains , Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain, TRAD.
Background: HAP1 (huntingtin-associated protein 1) binds to huntingtin (1). Huntingtin is a protein that contains a polyglutamine region and when the number of glutamine repeats exceeds 35, the gene encodes a version of huntingtin that leads to Huntington?s disease (HD) (2,3). The ability of HAP1 to bind to huntingtin is enhanced by an expanded polyglutamine repeat region (1). HAP1 shows neuronal localization and moves with huntingtin in nerve fibers (4,5). HAP1 is primarily expressed in brain tissue, with greater expression in the olfactory bulb and brain stem (1). Mouse HAP1 is localized to membrane-bound organelles including large endosomes, tubulovesicular structures and budding vesicles in neurons (6). Duo, also designated huntingtin-associated protein interacting protein or HAPIP, binds Huntingtin-associated protein 1 (HAP1) and may have a role in vesicle trafficking and cytoskeletal function.
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途径
- Neurotrophin Signaling Pathway
抗原
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