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ARHGEF25/GEFT 抗体 (AA 251-340) (HRP)

This anti-ARHGEF25/GEFT antibody is a 兔 多克隆 antibody detecting ARHGEF25/GEFT in WB, ELISA, IHC (p) 和 IHC (fro). Suitable for 大鼠.
产品编号 ABIN1411556
发货至: 中国

Quick Overview for ARHGEF25/GEFT 抗体 (AA 251-340) (HRP) (ABIN1411556)

抗原

See all ARHGEF25/GEFT (ARHGEF25) 抗体
ARHGEF25/GEFT (ARHGEF25) (Rho Guanine Nucleotide Exchange Factor 25 (ARHGEF25))

适用

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大鼠

宿主

  • 22
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克隆类型

  • 22
  • 1
多克隆

标记

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This ARHGEF25/GEFT antibody is conjugated to HRP

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 14
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 251-340

    交叉反应

    大鼠

    预测反应

    Human,Mouse,Cow,Sheep,Pig,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human GEFT

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    注意事项

    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    ARHGEF25/GEFT (ARHGEF25) (Rho Guanine Nucleotide Exchange Factor 25 (ARHGEF25))

    别名

    GEFT

    背景

    Synonyms: ARHGEF25, ARHGP_HUMAN, GEFT, p63RhoGEF, Guanine nucleotide exchange factor GEFT, p63RhoGEF , RAC/CDC42 exchange factor, Rac/Cdc42/Rho exchange factor GEFT, Rho guanine nucleotide exchange factor 25, RhoA/RAC/CDC42 exchange factor, RhoA/Rac/Cdc42 guanine nucleotide exchange factor GEFT.

    Background: GEFT is a 580 amino acid cytoplasmic protein that is highly expressed in excitable tissues such as brain, heart and muscle, and weakly expressed in small intestine, colon, liver, placenta and lung. GEFT may play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers. GEFT works as a guanine nucleotide exchange factor for the Rho family of small GTPases and links specifically to G alpha q/11-coupled receptors in Rho A activation. GEFT is an important regulator of processes involved in axon and dendrite formation. Involved in skeletal myogenesis, GEFT seems to be an exchange factor primarily for Rac 1 in neurons. Existing as two alternatively spliced variants, GEFT contains a DH (DBL-homology) domain and a PH domain.

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