Ataxin 10 抗体 (AA 21-120) (Cy7)
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Quick Overview for Ataxin 10 抗体 (AA 21-120) (Cy7) (ABIN1411326)
抗原
See all Ataxin 10 (ATXN10) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 21-120
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交叉反应
- 小鼠, 大鼠
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预测反应
- Human,Dog,Cow,Sheep,Pig,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human ATXN10/SCA10
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亚型
- IgG
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anti-Ataxin 10 (ATXN10) (AA 116-302) antibody
ATXN10 适用: 人 WB, IHC, FACS, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 10 (ATXN10) (AA 346-475) antibodyATXN10 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 10 (ATXN10) (AA 346-475) antibodyATXN10 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 10 (ATXN10) antibodyATXN10 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 10 (ATXN10) (AA 1-109) antibodyATXN10 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Ataxin 10 (ATXN10) (N-Term) antibodyATXN10 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 10 (ATXN10) (AA 1-475) antibodyATXN10 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Ataxin 10 (ATXN10) (C-Term) antibodyATXN10 适用: 人, 小鼠, 猴, 犬, 马, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 10 (ATXN10) (N-Term) antibodyATXN10 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- Ataxin 10 (ATXN10)
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别名
- ATXN10/SCA10
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背景
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Synonyms: Ataxin 10, Ataxin-10, ATX10_HUMAN, Atxn10, Brain protein E46 homolog, E46L, FLJ37990, HUMEEP, Like mouse brain protein E46, SCA10, Spinocerebellar ataxia 10, Spinocerebellar ataxia type 10 protein.
Background: Spinocerebellar ataxia (SCA) is an autosomal dominant neurodegenerative disorder characterized by ataxia and selective neuronal cell loss. SCA is caused by the expansion of a translated CAG repeat, encoding a polyglutamine tract in SCA gene products, known as ataxins. The ataxin proteins are ubiquitously expressed in nervous tissue, but are primarily detected in cerebellum, brain stem and spinal cord in the central nervous system. Ataxin-10 is a cytoplasmic protein that belongs to the family of armadillo repeat proteins. A loss of ataxin-10 in primary neuronal cells causes increased apoptosis of cerebellar neurons. Ataxin-10 interacts with p110, an O-Linked beta-N-acetylglucosamine transferase, and may be important in the regulation of intracellular glycosylation levels and homeostasis in the brain. Spinocerebellar ataxia type 10 (SCA10) is an autosomal dominant disorder that causes cerebellar ataxia and seizures. SCA10 is caused by an expansion of an ATTCT pentanucleotide repeat in intron 9 of the ataxin-10 gene.
抗原
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