AVPR1B 抗体 (AA 23-120) (Cy7)
Quick Overview for AVPR1B 抗体 (AA 23-120) (Cy7) (ABIN1411290)
抗原
See all AVPR1B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 23-120
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预测反应
- Human,Mouse,Rat,Dog,Cow,Pig,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human AVP Receptor V3
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亚型
- IgG
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anti-Arginine Vasopressin Receptor 1B (AVPR1B) (Cytoplasmic Domain) antibody
AVPR1B 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Arginine Vasopressin Receptor 1B (AVPR1B) (N-Term) antibodyAVPR1B 适用: 人, 大鼠, 犬, Cow, Pig, 马, 兔, Bat IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Arginine Vasopressin Receptor 1B (AVPR1B) (AA 271-320) antibodyAVPR1B 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Arginine Vasopressin Receptor 1B (AVPR1B) antibodyAVPR1B 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Arginine Vasopressin Receptor 1B (AVPR1B) (AA 224-284) antibodyAVPR1B 适用: 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Arginine Vasopressin Receptor 1B (AVPR1B) (AA 343-425) antibodyAVPR1B 适用: 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Arginine Vasopressin Receptor 1B (AVPR1B) (C-Term) antibodyAVPR1B 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Arginine Vasopressin Receptor 1B (AVPR1B) (AA 271-320) antibodyAVPR1B 适用: 人, 大鼠, 小鼠, 犬, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Arginine Vasopressin Receptor 1B (AVPR1B) (C-Term) antibodyAVPR1B 适用: 人 IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- AVPR1B (Arginine Vasopressin Receptor 1B (AVPR1B))
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别名
- AVPR1B/AVP Receptor V3
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背景
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Synonyms: Antidiuretic hormone receptor 1b, Arginine vasopressin receptor 1B, Arginine vasopressin receptor 3, AVPR V1b, AVPR V3, Avpr1b, AVPR3, Pituitary vasopressin receptor 3, V1bR, V1BR_HUMAN, Vasopressin V1b receptor, Vasopressin V3 receptor, VPR3.
Background: Vasopressin (AVP), the antidiuretic hormone, is a cyclic nonpeptide that is involved in the regulation of body fluid osmolality (1-3). AVP mediates its effects through a family of G-protein coupled receptors, the vasopressin receptors type V1a, V2 and V3 (also designated V1b) (1,2). The AVP receptor V1a is responsible for several functions, including blood vessel constriction, liver glycogenolysis and platelet adhesion (3). It is detected as a full length protein and a shorter protein, which results from proteolytic cleavage of its amino terminus (4). The V1a receptor is coupled to Gq/11 protein, which increases the intracellular calcium concentration (3). The human AVP receptor V2 gene maps to chromosome Xq28 and is expressed in lung and kidney (5,6). Mutations in the V2 receptor result in nephrogenic diabetes insipidus (NDI), a rare X-linked disorder characterized by the inability of the kidney to concentrate urine in response to AVP (5,7). The AVP Receptor V2 activates the Gs protein and the cyclic AMP second messenger system (7). The AVP receptor V3 is preferentially expressed in the pituitary and stimulates the release of adrenocorticotropic hormone (ACTH) in response to AVP by mobilizing intracellular calcium stores (8). AVP receptor antagonists may have potential therapeutic effects in hypertension, congestive heart failure, nephrotic syndrome and ACTH-secreting tumors (2).
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途径
- Regulation of Systemic Arterial Blood Pressure by Hormones
抗原
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