ALS2 抗体 (AA 1384-1440) (Cy7)
Quick Overview for ALS2 抗体 (AA 1384-1440) (Cy7) (ABIN1410768)
抗原
See all ALS2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1384-1440
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预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human ALS2
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亚型
- IgG
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anti-Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2) (AA 1-280) antibody
ALS2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2) (AA 1-280) antibodyALS2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2) (AA 221-320) antibodyALS2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4F10 unconjugated
anti-Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2) antibodyALS2 适用: 人, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2) (AA 1-1237) antibodyALS2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2) (C-Term) antibodyVerified ALS2 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2) (AA 1-1237) antibodyALS2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2) (N-Term) antibodyALS2 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2) (AA 1007-1056) antibodyALS2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, Bat, 小鸡, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2) (AA 1248-1277), (C-Term) antibodyALS2 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB18853 unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- ALS2 (Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2))
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别名
- ALS2/Alsin
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背景
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Synonyms: ALS 2, ALS2, ALS2_HUMAN, ALS2CR6, Alsin, ALSJ, Amyotrophic lateral sclerosis 2 juvenile, Amyotrophic lateral sclerosis 2 juvenile chromosome region candidate 6, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein, Amyotrophic lateral sclerosis 2 protein, Amyotrophic lateral sclerosis protein 2, FLJ31851, IAHSP, KIAA1563, MGC87187, PLSJ.
Background: Mutations in the ALS2 gene result in a number of juvenile recessive motor neuron diseases (MNDs), including juvenile primary lateral sclerosis (JPLS), a recessive form of amyotrophic lateral sclerosis (ALS2), infantile onset ascending hereditary spastic paralysis (IAHSP), and a form of complicated hereditary spastic paraplegia (cHSP). The ALS2 gene encodes the Alsin protein. Alsin acts as a guanine nucleotide exchange factor for Rab5, a modulator of the endocytic pathway. Alsin is a cytosolic protein that is associated with small, punctate membrane structures. Therefore, Alsin may mediate membrane transport events, potentially linking endocytic processes and actin cytoskeleton remodeling. The ALS2 C-terminal-like protein (ALS2CL) also modulates Rab 5 activity.
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途径
- Skeletal Muscle Fiber Development
抗原
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