FICD 抗体 (AA 161-250) (Cy3)
Quick Overview for FICD 抗体 (AA 161-250) (Cy3) (ABIN1410699)
抗原
See all FICD 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 161-250
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交叉反应
- 小鼠
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预测反应
- Human,Rat,Dog,Sheep,Pig,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human HYPE
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亚型
- IgG
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anti-FIC Domain Containing (FICD) (AA 63-185) antibody
FICD 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-FIC Domain Containing (FICD) (AA 1-449) antibodyFICD 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3F5 unconjugated
anti-FIC Domain Containing (FICD) (AA 1-458) antibodyFICD 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-FIC Domain Containing (FICD) (C-Term) antibodyFICD 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-FIC Domain Containing (FICD) (C-Term) antibodyFICD 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 豚鼠, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-FIC Domain Containing (FICD) (AA 161-250) antibodyFICD 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-FIC Domain Containing (FICD) (C-Term) antibodyFICD 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, Pig, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-FIC Domain Containing (FICD) (AA 351-400) antibodyFICD 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 豚鼠, Pig, 兔, Bat, 猴, Drosophila melanogaster, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-FIC Domain Containing (FICD) (C-Term) antibodyFICD 适用: 人, 小鼠, 大鼠, 犬 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- FICD (FIC Domain Containing (FICD))
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别名
- HYPE/HIP13
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背景
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Synonyms: Adenosine monophosphate-protein transferase FICD, AMPylator FICD, FIC domain containing, FIC domain containing protein, FIC domain-containing protein, Fic S phase protein cell division homolog, ficd, FICD_HUMAN, HIP-13, HIP13, Huntingtin interacting protein 13, Huntingtin interacting protein E, Huntingtin interactor protein E, Huntingtin yeast partner E, Huntingtin-interacting protein 13, Huntingtin-interacting protein E.
Background: Huntingtin yeast partner E is a 458 amino acid single-pass membrane protein. HYPE is thought to interact with Huntingtin, a protein which induces neurodegeneration when mutated. HYPE also contains two tetratricopeptide repeats (TPR), which may be involved in protein-protein interaction. The gene that encodes HYPE is located on chromosome 12, which encodes over 1,100 genes within 132 million bases and makes up about 4.5 % of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy.
抗原
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