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RCAN3 抗体 (AA 151-241) (Cy3)

RCAN3 适用: 小鼠, 大鼠 WB, IF (cc), IF (p) 宿主: 兔 Polyclonal Cy3
产品编号 ABIN1409775
发货至: 中国
  • 抗原 See all RCAN3 抗体
    RCAN3 (RCAN Family Member 3 (RCAN3))
    抗原表位
    • 15
    • 14
    • 9
    • 7
    • 6
    • 3
    • 1
    AA 151-241
    适用
    • 41
    • 31
    • 15
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    小鼠, 大鼠
    宿主
    • 54
    • 1
    克隆类型
    • 54
    • 1
    多克隆
    标记
    • 15
    • 6
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This RCAN3 antibody is conjugated to Cy3
    应用范围
    • 41
    • 30
    • 21
    • 12
    • 12
    • 5
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    小鼠, 大鼠
    预测反应
    Human,Dog,Cow,Sheep,Pig,Chicken,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Calcipressin 3
    亚型
    IgG
    Top Product
    Discover our top product RCAN3 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    RCAN3 (RCAN Family Member 3 (RCAN3))
    别名
    Calcipressin 3 (RCAN3 产品)
    别名
    DSCR1L2 antibody, rcn3 antibody, hrcn3 antibody, mcip3 antibody, dscr1l2 antibody, MGC145788 antibody, MCIP3 antibody, RCN3 antibody, hRCN3 antibody, Dscr1l2 antibody, AU041093 antibody, Csp3 antibody, wu:fc68f05 antibody, zgc:113155 antibody, zgc:91820 antibody, RCAN family member 3 antibody, calcipressin-3 antibody, regulator of calcineurin 3 antibody, RCAN3 antibody, Tsp_08182 antibody, rcan3 antibody, Rcan3 antibody
    背景

    Synonyms: Calcipressin-3, Down syndrome candidate region 1 like 2, regulator of calcineurin 3, Down syndrome candidate region 1 like protein 2, Down syndrome candidate region 1-like protein 2, Down syndrome critical region gene 1 like 2, DSCR1L2, hRCN3, MCIP3, Myocyte enriched calcineurin interacting protein 3, Myocyte-enriched calcineurin-interacting protein 3, RCAN family member 3, RCAN3, RCAN3_HUMAN, RCN3, Regulator of calcineurin 3.

    Background: Calcineurin is a Ca(2+) dependent protein phosphatase that is involed in several neuornal functions. Proteins belonging to the RCAN (Regulator of calcineurin) family modulate the activity of Calcineurin through a valine-rich region within their carboxyl tail. RCANs compete with NFATs (Nuclear factor of activated T-cells) for binding to the same docking site in calcineurin, which results in either inhibition or activation of calcineurin activity. Calcipressin-2, also known as RCAN2 and DSCR1L1 (Down syndrome candidate region 1-like 1), is a 197 amino acid protein that is highly expressed in both the cytoplasm and nucleus of neurons and is the only RCAN family member that is found in glial cells. Calcipressin-3, also known as RCAN3 and DSCR1L2 (Down syndrome candidate region 1-like protein 2), is a 241 amino acid protein that potentially is involved in central nervous system development. Calcipressin-3 interacts with cardiac troponin I, suggesting that it may play a role in cardiac contraction events.

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