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BBS10 抗体 (AA 51-130) (Cy3)

BBS10 适用: 人 WB, IF (cc), IF (p) 宿主: 兔 Polyclonal Cy3
产品编号 ABIN1409595
发货至: 中国
  • 抗原 See all BBS10 抗体
    BBS10 (Bardet-Biedl Syndrome 10 (BBS10))
    抗原表位
    • 14
    • 8
    • 8
    • 6
    • 4
    • 2
    • 1
    • 1
    AA 51-130
    适用
    • 39
    • 2
    • 1
    • 1
    宿主
    • 38
    • 1
    克隆类型
    • 39
    多克隆
    标记
    • 13
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BBS10 antibody is conjugated to Cy3
    应用范围
    • 35
    • 20
    • 13
    • 12
    • 12
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    预测反应
    Human,Mouse,Rat
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human BBS10
    亚型
    IgG
    Top Product
    Discover our top product BBS10 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    BBS10 (Bardet-Biedl Syndrome 10 (BBS10))
    别名
    BBS10 (BBS10 产品)
    别名
    MGC84945 antibody, si:dkey-30c15.16 antibody, C12orf58 antibody, RGD1560748 antibody, 1300007O09Rik antibody, AI452285 antibody, Bardet-Biedl syndrome 10 antibody, Bardet-Biedl syndrome 10 L homeolog antibody, Bardet-Biedl syndrome 10 (human) antibody, BBS10 antibody, bbs10.L antibody, bbs10 antibody, Bbs10 antibody
    背景

    Synonyms: Bardet Biedl syndrome 10 protein, Bardet Biedl syndrome 10 protein homolog, C12orf58, FLJ23560, RGD1560748, BBS10_HUMAN.

    Background: Bardet-Biedl syndrome (BBS) is a pleiotropic genetic disorder characterized by obesity, photoreceptor degeneration, polydactyly, hypogenitalism, renal abnormalities, and developmental delay. Other associated clinical findings in BBS patients include diabetes, hypertension, and congenital heart defects. BBS genes map to multiple loci and encode fourteen proteins, BBS1-BBS14. Many BBS genes encode basal body or cilia proteins, suggesting that BBS is a ciliary dysfunction disorder. BBS10 (Bardet-Biedl syndrome 10), also known as chromosome 12 open reading fame 58, C12orf58 or FLJ23560, is a novel 723 amino acid protein belonging to the TCP-1 chaperonin family. BBS10 localizes to the basal body of primary cilium and assists in protein folding upon ATP hydrolysis. Inhibition of BBS10 has been found to impair ciliogenesis, activate the glycogen synthase kinase 3 pathway and cause peroxisome proliferator-activated receptor nuclear accumulation. The gene encoding BBS10 contains two exons and maps to human chromosome 12q21.2.

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