THRB 抗体 (AA 201-300) (Cy7)
Quick Overview for THRB 抗体 (AA 201-300) (Cy7) (ABIN1409184)
抗原
See all THRB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 201-300
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Cow,Sheep,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Thyroid Hormone Receptor beta
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亚型
- IgG
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anti-Thyroid Hormone Receptor, beta (THRB) (AA 1-169) antibody
THRB 适用: 人 WB, IHC, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Hormone Receptor, beta (THRB) (AA 1-461) antibodyTHRB 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Hormone Receptor, beta (THRB) (AA 239-457) antibodyTHRB 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Hormone Receptor, beta (THRB) (AA 37-86) antibodyTHRB 适用: 人, 大鼠, 马, 犬, 豚鼠, 兔, 猴, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Hormone Receptor, beta (THRB) (AA 1-250) antibodyTHRB 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Hormone Receptor, beta (THRB) (N-Term) antibodyTHRB 适用: 人 WB 宿主: 小鼠 Monoclonal 2386 unconjugated
anti-Thyroid Hormone Receptor, beta (THRB) (N-Term) antibodyTHRB 适用: 人, 小鼠, 大鼠, 马, 犬, 兔, 绵羊 WB, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Hormone Receptor, beta (THRB) (N-Term) antibodyTHRB 适用: 人, 小鼠, 大鼠, 马, 豚鼠, Cow WB, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Hormone Receptor, beta (THRB) (AA 391-440) antibodyTHRB 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Hormone Receptor, beta (THRB) (N-Term) antibodyTHRB 适用: 人, 小鼠 WB, ELISA, IF, IP, FM 宿主: 兔 Polyclonal unconjugated
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应用备注
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- THRB (Thyroid Hormone Receptor, beta (THRB))
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别名
- THRB
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背景
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Synonyms: Thyroid Hormone Receptor beta, Avian erythroblastic leukemia viral v erb a oncogene homolog 2, C ERBA 2, C ERBA BETA, c-erbA-2, c-erbA-beta, ERBA 2, ERBA BETA, ERBA2, Erythroblastic leukemia viral v erb a oncogene homolog 2 avian, generalized resistance to thyroid hormone, GRTH, MGC126109, MGC126110, NR1A2, Nuclear receptor subfamily 1 group A member 2, Oncogene ERBA2, PRTH, THB_HUMAN, THR 1, THR1, THRB 1,
Background: Thyroid hormone receptors (TRs) are ligand-dependent transcription factors that mediate the biological activities of thyroid hormone (T3). Thyroid hormone receptor b2 (TRb2) is a high affinity receptor for triiodothyronine which belongs to the nuclear hormone receptor family and the NR1 subfamily. It is composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal steroid-binding domain. Defects in the receptor result in generalized thyroid hormone resistance (GTHR). GTHR is transmitted as an autosomal dominant trait, but an autosomal recessive form also exists. The disease is characterized by goiter, abnormal mental functions, increased susceptibility to infections, abnormal growth and bone maturation, tachycardia and deafness. GTHR patients also have high levels of circulating thyroid hormones (T3-T4), with normal or slightly elevated thyroid stimulating hormone.
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基因ID
- 7068
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UniProt
- P10828
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途径
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Sensory Perception of Sound
抗原
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