NMUR1 抗体 (AA 31-80) (HRP)
Quick Overview for NMUR1 抗体 (AA 31-80) (HRP) (ABIN1409066)
抗原
See all NMUR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 31-80
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Cow,Sheep,Pig,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human NMUR1
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亚型
- IgG
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应用备注
- IHC-P 1:200-400
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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注意事项
- Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- NMUR1 (Neuromedin U Receptor 1 (NMUR1))
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别名
- NMUR1/GPR66
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背景
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Synonyms: FM-3, G protein-coupled receptor 66, G-protein coupled receptor 66, G-protein coupled receptor FM-3, GPR66, Growth hormone secretagogue receptor family Member 3, Neuromedin U Receptor 1, Neuromedin-U receptor 1, NMU-R1, NMUR1, NMUR1_HUMAN.
Background: Neuromedin U is a neuropeptide with high activity on smooth muscle. It is widely expressed in gastrointestinal systems and central nervous system (CNS). Peripheral activities of neuromedin U include smooth muscle stimulation, ion transport alterations in the gut and the regulation of local blood flow and adrenocortical function. Neuromedin U receptors 1 and 2 (NMUR1 and NMUR2) are multi-pass membrane proteins that belong to the G-protein coupled receptor 1 family of proteins. Both NMUR1 and NMUR2 act as receptors for the neuromedin U neuropeptide. NMUR1 is detected in peripheral organs, particularly in urogenital and gastrointestinal systems, with highest levels in testis. It?s expression in CNS is low, but the protein has been detected in cerebellum, hippocampus, dorsal root ganglia and spinal cord. NMUR2 is predominantly detected in central nervous system with highest levels detected in medulla oblongata, spinal cord and thalamus. It may also be detected in testis but has low levels of expression in peripheral tissues.
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基因ID
- 10316
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UniProt
- Q9HB89
抗原
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