AACS 抗体 (AA 182-228) (Cy3)
Quick Overview for AACS 抗体 (AA 182-228) (Cy3) (ABIN1408839)
抗原
See all AACS 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 182-228
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预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human AACS
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亚型
- IgG
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anti-Acetoacetyl-CoA Synthetase (AACS) (AA 435-598) antibody
AACS 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Acetoacetyl-CoA Synthetase (AACS) (AA 1-410) antibodyAACS 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Acetoacetyl-CoA Synthetase (AACS) (AA 539-573), (C-Term) antibodyAACS 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal RB51965 unconjugated
anti-Acetoacetyl-CoA Synthetase (AACS) (AA 1-410) antibodyAACS 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- AACS (Acetoacetyl-CoA Synthetase (AACS))
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别名
- AACS/ACSF1
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背景
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Synonyms: Acetoacetyl-CoA synthetase, ACSF1, Acyl-CoA synthetase family member 1, Protein sur-5 homolog, AACS_HUMAN.
Background: ACSF1 is a 672 amino acid protein belonging to the ATP-dependent AMP-binding enzyme family. Encoded by a gene that maps to human chromosome 12q24.31, ACSF1 is highly expressed in kidney, heart and brain, and shows similar neural expression as HMGCR (3-hydroxy-3-methylglutaryl-CoA reductase). Existing as three alternatively spliced isoforms, ACSF1 participates in ATP binding, ligase activity, acetoacetate-CoA ligase activity and nucleotide binding. The ACSF1 promoter is a known PPAR?target gene, with the nuclear receptor recruited to the ACSF1 promoter by direct interaction with stimulating protein-1 (Sp1). ACSF1 activates acetoacetate and is highly regulated by modulators that affect HMGCR and cholesterol biosynthesis.
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基因ID
- 65985
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途径
- Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis
抗原
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