SNAPIN 抗体 (AA 51-136) (HRP)
Quick Overview for SNAPIN 抗体 (AA 51-136) (HRP) (ABIN1408730)
抗原
See all SNAPIN 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 51-136
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预测反应
- Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human SNAP25BP
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亚型
- IgG
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应用备注
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IHC-P 1:200-400
IHC-F 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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注意事项
- Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- SNAPIN (SNAP-Associated Protein (SNAPIN))
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别名
- SNAPIN/SNAP25BP
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背景
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Synonyms: SNAP associated protein, SNAP-25-binding protein, SNAP-associated protein, SNAP25BP, SNAPAP, SNAPIN, SNAPN_HUMAN, SNARE associated protein snapin, SNARE-associated protein Snapin, Synaptosomal associated protein 25 binding protein, Synaptosomal-associated protein 25-binding protein, OTTHUMP00000035157.
Background: The protein encoded by this gene is a coiled-coil-forming protein that associates with the SNARE (soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor) complex of proteins and the BLOC-1 (biogenesis of lysosome-related organelles) complex. Biochemical studies have identified additional binding partners. As part of the SNARE complex, it is required for vesicle docking and fusion and regulates neurotransmitter release. The BLOC-1 complex is required for the biogenesis of specialized organelles such as melanosomes and platelet dense granules. Mutations in gene products that form the BLOC-1 complex have been identified in mouse strains that are models of Hermansky-Pudlak syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012].
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基因ID
- 23557
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途径
- Synaptic Membrane, Synaptic Vesicle Exocytosis
抗原
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