ATXN7 抗体 (AA 301-400) (Cy7)
Quick Overview for ATXN7 抗体 (AA 301-400) (Cy7) (ABIN1408452)
抗原
See all ATXN7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 301-400
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交叉反应
- 小鼠, 大鼠
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预测反应
- Human,Dog,Cow,Sheep,Pig,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Ataxin 7
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亚型
- IgG
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anti-Ataxin 7 (ATXN7) (AA 402-503) antibody
ATXN7 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 7 (ATXN7) antibodyATXN7 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 7 (ATXN7) (Internal Region) antibodyATXN7 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 7 (ATXN7) (AA 359-408) antibodyATXN7 适用: 人, 小鼠, 豚鼠, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 7 (ATXN7) (Middle Region) antibodyATXN7 适用: 人, 小鼠, 大鼠, 犬, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 7 (ATXN7) (Middle Region) antibodyATXN7 适用: 人, 小鼠, 大鼠, 兔, 犬, 豚鼠, 马, Cow, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- ATXN7 (Ataxin 7 (ATXN7))
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别名
- Ataxin 7
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背景
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Synonyms: Ataxin7, Ataxin-7, ADCAII, ATXN 7, OPCA III, OPCA3, SCA 7, SCA7, Spinocerebellar Ataxia 7, Spinocerebellar ataxia type 7 protein, ATX7_HUMAN.
Background: The human ataxin-7 gene, also known as spinocerebellar ataxia 7 or SCA7, maps to chromosome 3p13-p12, has a 2,727-bp open reading frame, and encodes a 892 amino acid protein containing a nuclear localization signal and a polyglutamine tract (1,2). SCA7 is an autosomal dominant neurodegenerative disorder characterized by ataxia and selective neuronal cell loss caused by the expansion of a translated CAG repeat encoding a polyglutamine tract in ataxin-7, which is the SCA7 gene product (3,4). Ataxin-7 is expressed within neurons both affected and unaffected in SCA7 pathology with subcellular localization being variable depending upon the neuronal subtype (5). Polyglutamine expanded in ataxin-7 may carry out its pathogenic effects in the nucleus by altering the matrix-associated nuclear structure and/or by disrupting nucleolar function (6).
抗原
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