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NAB2 抗体 (Cy5.5)

This anti-NAB2 antibody is a 兔 多克隆 antibody detecting NAB2 in WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN1408337
发货至: 中国

Quick Overview for NAB2 抗体 (Cy5.5) (ABIN1408337)

抗原

See all NAB2 抗体
NAB2 (NGFI-A Binding Protein 2 (EGR1 Binding Protein 2) (NAB2))

适用

  • 45
  • 33
  • 26
  • 7
  • 6
  • 6
  • 5
  • 5
  • 5
  • 3
  • 3
  • 2
人, 小鼠, 大鼠

宿主

  • 43
  • 6

克隆类型

  • 45
  • 4
多克隆

标记

  • 29
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This NAB2 antibody is conjugated to Cy5.5

应用范围

  • 42
  • 13
  • 9
  • 7
  • 5
  • 3
  • 3
  • 1
Western Blotting (WB)
  • 交叉反应

    小鼠

    预测反应

    Human,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human NAB2

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    NAB2 (NGFI-A Binding Protein 2 (EGR1 Binding Protein 2) (NAB2))

    别名

    Nab2/Mader

    背景

    Synonyms: EGR 1 binding protein 2, EGR-1-binding protein 2, EGR1 binding protein 2, MADER, Melanoma associated delayed early response protein, Melanoma-associated delayed early response protein, MGC75085, Nab 2, nab2, NAB2_HUMAN, NGFI A binding protein 2 EGR1 binding protein 2, NGFI A binding protein 2, NGFI-A-binding protein 2, Protein MADER.

    Background: Transcriptional control is in part regulated by interactions between DNA-bound transcription factors, such as Egr-1/NGFI-A, and coregulatory proteins, such as NAB (for NGFI-A-binding proteins). The evolutionarily conserved NAB proteins, NAB1 and NAB2 are corepressors of EGF-1/NGFI-A. Both NAB1 and NAB2 contain an amino terminal NAB conserved domain 1 (NCB1), which is required for binding NGFI-A, and a carboxy terminal NCD2 domain, which is responsible for the repressor function of NAB proteins. NAB2 is principally localized in the nucleus and may play a role in the downregulation of NGFI-A activity as well as in controlling fundamental processes such as cell division, differentiation and apoptosis. NAB2 localizes to chromosome 12q13.3-14.1, a region that is rearranged in several solid tumors, lipomas, and liposarcomas.

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