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Endothelin 2 抗体 (AA 49-59) (Cy7)

This anti-Endothelin 2 antibody is a 兔 多克隆 antibody detecting Endothelin 2 in IF (cc) 和 IF (p). Suitable for Cat.
产品编号 ABIN1408224
发货至: 中国

Quick Overview for Endothelin 2 抗体 (AA 49-59) (Cy7) (ABIN1408224)

抗原

See all Endothelin 2 (EDN2) 抗体
Endothelin 2 (EDN2)

适用

  • 38
  • 14
  • 6
  • 5
  • 2
  • 1
  • 1
  • 1
  • 1
Cat

宿主

  • 49
  • 5

克隆类型

  • 50
  • 4
多克隆

标记

  • 24
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Endothelin 2 antibody is conjugated to Cy7

应用范围

  • 24
  • 15
  • 12
  • 12
  • 12
  • 10
  • 7
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 1
Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
    • 8
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    AA 49-59

    交叉反应

    Cat

    预测反应

    Human,Mouse,Rat,Dog,Cow,Cat,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Endolin 2

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    Endothelin 2 (EDN2)

    别名

    ET-2/Endothelin 2

    背景

    Synonyms: EDN2, EDN2_HUMAN, Endothelin 2, Endothelin-2, ET 2, ET-2, ET2, PPET2, Preproendothelin 2, Preproendothelin-2.

    Background: The endothelin (ET) family of proteins, which includes ET-1 (endothelin-1), ET-2 (endothelin-2) and ET-3 (endothelin-3), are vasoactive peptides that are involved in various functions throughout the body. Endothelins can affect the central nervous system and neuronal excitability, and they elicit potent vasoconstrictor action. While ET-1 is a potent, 21-amino acid vasoconstrictor peptide, ET-2 has the most potent vasoconstrictor activity. ET-3 functions as a ligand for endothelin receptor type B (ETBR) and, through this interaction, mediates the maturation of enteric neurons and melanocytes. Although ET-3 is expressed as a 238 amino acid peptide, it is post-translationally modified to produce a short active isoform and a long inactive isoform. Defects in the gene encoding ET-3 are the cause of a variety of disorders, including Hirschsprung disease type 1 (HSCR1), congenital central hypoventilation syndrome (CCHS) and Waardenburg syndrome type IV (WS4).

    途径

    Hormone Activity, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones
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