DERL1 抗体 (AA 111-220) (Cy5)
Our Local Distributor
北京 101111
Quick Overview for DERL1 抗体 (AA 111-220) (Cy5) (ABIN1408150)
抗原
See all DERL1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 111-220
-
交叉反应
- 人
-
预测反应
- Mouse,Rat,Dog,Cow,Sheep,Horse,Rabbit
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human DERLIN-1
-
亚型
- IgG
-
-
anti-Der1-Like Domain Family, Member 1 (DERL1) (AA 224-251), (C-Term) antibody
DERL1 适用: 人, 小鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB22770 unconjugated
anti-Der1-Like Domain Family, Member 1 (DERL1) (AA 111-220) antibodyDERL1 适用: 人 ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Der1-Like Domain Family, Member 1 (DERL1) (AA 224-251) antibodyDERL1 适用: 人, 小鼠 WB, IHC, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
anti-Der1-Like Domain Family, Member 1 (DERL1) (AA 222-251), (C-Term) antibodyDERL1 适用: 人, 小鼠 WB, IHC (p), FACS, EIA 宿主: 兔 Polyclonal unconjugated
anti-Der1-Like Domain Family, Member 1 (DERL1) (AA 200-251), (C-Term) antibodyDERL1 适用: 人, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
-
有效期
- 12 months
-
-
- DERL1 (Der1-Like Domain Family, Member 1 (DERL1))
-
别名
- DERLIN-1
-
背景
-
Synonyms: Derlin1, Derlin1, Derlin 1, DER1, DER-1, DER 1, DERL1_HUMAN.
Background: Degradation in endoplasmic reticulum proteins, also designated Derlins or DERtrins, are crucial for the degradation of misfolded endoplasmic reticulum (ER) luminal proteins. Derlin proteins are multi-pass membrane proteins localizing to the ER. Derlins are involved in transferring misfolded proteins from the ER to the cytosol, where the misfolded proteins are destroyed in an ubiquitin-dependent manner by the proteasome. In the case of cytomegalovirus infection, Derlin-1, as opposed to Derlins-2 and -3, is involved in the export of MHC class I heavy chains from the ER via its interaction with the viral protein US11. Derlins may also be important for cell proliferation.
-
基因ID
- 79139
-
UniProt
- Q9BUN8
-
途径
- ER-Nucleus Signaling
抗原
-
