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CCT2 抗体 (AA 131-230) (HRP)

This anti-CCT2 antibody is a 兔 多克隆 antibody detecting CCT2 in WB, ELISA, IHC (p) 和 IHC (fro). Suitable for 人 和 小鼠.
产品编号 ABIN1408148
发货至: 中国

Quick Overview for CCT2 抗体 (AA 131-230) (HRP) (ABIN1408148)

抗原

See all CCT2 抗体
CCT2 (Chaperonin Containing TCP1, Subunit 2 (Beta) (CCT2))

适用

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  • 42
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  • 8
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  • 6
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  • 5
  • 5
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 53
  • 16
  • 1

克隆类型

  • 49
  • 21
多克隆

标记

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  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
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  • 1
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This CCT2 antibody is conjugated to HRP

应用范围

  • 57
  • 24
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  • 17
  • 13
  • 13
  • 9
  • 8
  • 8
  • 4
  • 2
  • 2
  • 1
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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 14
    • 8
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 131-230

    交叉反应

    人, 小鼠

    预测反应

    Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit,Zebrafish

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human CCT2/TCP1 beta

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    注意事项

    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    CCT2 (Chaperonin Containing TCP1, Subunit 2 (Beta) (CCT2))

    别名

    CCT2/TCP1 beta

    背景

    Synonyms: CCT 2, CCT beta, CCT-beta, CCT-2, CCTB, Chaperonin containing t complex polypeptide 1 beta subunit, Chaperonin containing t complex polypeptide 1 subunit 2, Chaperonin containing TCP1 subunit 2, Chaperonin containing TCP1 subunit 2 beta, CTP:phosphocholine cytidylyltransferase 2, MGC142074, MGC142076, MGC94480, PRO1633, T complex protein 1 beta subunit, T complex protein 1 subunit beta, T-complex protein 1 subunit beta, TCP 1 beta, TCP-1-beta, TCPB_HUMAN, 99D8.1.

    Background: CCT2 is one of eight largely unrelated subunit proteins found in a protein chaperone complex known as the chaperonin-containing TCP-1 (CCT) or TRiC complex. The CCT complex is an abundanct cytoslic component that is credited with helping newly synthesized polypeptides adopt the correct conformation (1). Proteins that fold and assemble with the help of CCT include the cytoskeletal proteins actin and tubulin as well as up to 15 % of newly synthesized eukaryotic proteins (2). CCT2 is the _-subunit of the chaperone complex and is one of several CCT proteins that exhibit increased expression in response to stress. This implies that the CCT complex helps cells recover from protein damage by assisting in protein folding and assembly (3). CCT subunit levels also change throughout the cell cycle, with lower proteins levels (and reduced chaperone activity) found during induced cell cycle arrest during at M phase (4). Each CCT subunit is thought to perform a specific function during protein folding and assembly (5), CCT2 exhibits both actin and tubulin binding activities (6,3) but the exact molecular function on this subunit remains uncertain.

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