Myosin VI 抗体 (AA 1101-1294) (Cy3)
Quick Overview for Myosin VI 抗体 (AA 1101-1294) (Cy3) (ABIN1408131)
抗原
See all Myosin VI (MYO6) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1101-1294
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交叉反应
- 小鼠, 大鼠
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预测反应
- Human,Dog,Cow,Sheep,Pig,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Myosin VI
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亚型
- IgG
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anti-Myosin VI (MYO6) (N-Term) antibody
MYO6 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Myosin VI (MYO6) (AA 1188-1285) antibodyMYO6 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E12 unconjugated
anti-Myosin VI (MYO6) (AA 1166-1195), (C-Term) antibodyMYO6 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB19127 unconjugated
anti-Myosin VI (MYO6) (AA 1173-1203), (C-Term) antibodyMYO6 适用: 人 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Myosin VI (MYO6) (N-Term) antibodyMYO6 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Myosin VI (MYO6) (AA 1016-1285) antibodyMYO6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- Myosin VI (MYO6)
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别名
- MYO6/Myosin VI
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背景
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Synonyms: Deafness autosomal recessive 37, DFNA 22, DFNA22, DFNB 37, DFNB37, KIAA0389, MYO 6, Myo6, MYO6_HUMAN, Myosin 6, Myosin VI, Myosin-VI, Myosin6, MyosinVI, Unconventional myosin-6.
Background: Myosin VI a molecular motor involved in intracellular vesicle and organelle transport, is the only Myosin motor that binds to the pointed end of Actin. This unique Myosin has only one light chain in the lever-arm domain and has highly irregular stepping with a wide range of step sizes, unlike that of other characterized Myosins. It associates with Clathrin-coated vesicles and disabled 2, indicating a role for Myosin VI in endocytosis. Mouse Myosin VI is expressed within the sensory hair cells of the cochlea. Human Myosin VI is mapped to the centromeric region of chromosome 6, a region that shows syntenic homology with the corresponding mouse chromosome 9 region, where the Snell?s Waltzer mutation is located. The behavioral effects of the mouse Snell?s Waltzer mutation are lack of responsiveness to sound, hyperactivity, head tossing and circling, due to the disorganization and fusing of stereocilia bundles within the inner ear. Defects of Myosin VI cause autosomal dominant nonsyndromic sensori-neural deafness in humans. Human Myosin VI is expressed in fetal cochlea and brain, as well as in adult brain.
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途径
- Sensory Perception of Sound, Dicarboxylic Acid Transport, Asymmetric Protein Localization
抗原
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