TMED10 抗体 (AA 101-200) (Cy7)
Quick Overview for TMED10 抗体 (AA 101-200) (Cy7) (ABIN1408122)
抗原
See all TMED10 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 101-200
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特异性
- KO-Validated
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交叉反应
- 人, 小鼠
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预测反应
- Rat,Dog,Cow,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human TMP21
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亚型
- IgG
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- TMED10 (Transmembrane Emp24-Like Trafficking Protein 10 (TMED10))
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别名
- TMP21
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背景
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Synonyms: p23, p24 family protein delta 1, p24delta, p24delta1, S31I125, S31III125, TMED 10, TMED10, Tmp 21 I, Tmp 21, Tmp 21 I, Transmembrane emp24 domain containing protein 10, Transmembrane emp24-like trafficking protein 10 yeast, Transmembrane protein Tmp21, Transmembrane trafficking protein 21kD, 1110014C03Rik, 21 kDa transmembrane trafficking protein, MGC102351, TMEDA_HUMAN.
Background: MP21 is a member of the EMP24/GP25L/p24 cargo family of proteins that regulates vesicular trafficking in the early secretory pathway. TMP21 is a ubiquitously expressed single-pass type I membrane protein localizing to the Golgi cisternae and the plasma membrane. It contains one GOLD (Golgi dynamics) domain and participates in protein transport and quality control between the endoplasmic reticulum (ER) and the Golgi complex. In addition, TMP21 is a component of the heteromeric secretase complex (or Presenilin complex) and functions to regulate the ?secretase activity. Two isoforms, namely TMP21-I and TMP21-II, exist for this protein.
抗原
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