SHANK2 抗体 (AA 161-260) (Cy3)
Quick Overview for SHANK2 抗体 (AA 161-260) (Cy3) (ABIN1407981)
抗原
See all SHANK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 161-260
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交叉反应
- 小鼠
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预测反应
- Human,Rat,Dog,Cow,Sheep,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human SHANK2
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亚型
- IgG
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anti-SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2) (AA 84-309) antibody
SHANK2 适用: 大鼠 WB, IHC, IP, ICC, IF, AA 宿主: 小鼠 Monoclonal N23b-49 (Formerly S23b-49) unconjugated
anti-SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2) (AA 84-309) antibody (HRP)SHANK2 适用: 大鼠 WB, IHC, IP, ICC, IF, AA 宿主: 小鼠 Monoclonal N23b-49 (Formerly S23b-49) HRP
anti-SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2) (AA 84-309) antibody (FITC)SHANK2 适用: 大鼠 WB, IHC, IP, ICC, IF, AA 宿主: 小鼠 Monoclonal N23b-49 (Formerly S23b-49) FITC
anti-SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2) (AA 84-309) antibody (Biotin)SHANK2 适用: 大鼠 WB, IHC, IP, ICC, IF, AA 宿主: 小鼠 Monoclonal N23b-49 (Formerly S23b-49) Biotin
anti-SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2) (AA 84-309) antibody (PE)SHANK2 适用: 大鼠 WB, IHC, IP, ICC, IF, AA 宿主: 小鼠 Monoclonal N23b-49 (Formerly S23b-49) PE
anti-SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2) (AA 84-309) antibody (PerCP)SHANK2 适用: 大鼠 WB, IHC, IP, ICC, IF, AA 宿主: 小鼠 Monoclonal N23b-49 (Formerly S23b-49) PerCP
anti-SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2) (AA 84-309) antibody (APC)SHANK2 适用: 大鼠 WB, IHC, IP, ICC, IF, AA 宿主: 小鼠 Monoclonal N23b-49 (Formerly S23b-49) APC
anti-SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2) (AA 84-309) antibody (Atto 594)SHANK2 适用: 大鼠 WB, IHC, IP, ICC, IF, AA 宿主: 小鼠 Monoclonal N23b-49 (Formerly S23b-49) Atto 594
anti-SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2) (AA 84-309) antibody (Atto 488)SHANK2 适用: 大鼠 WB, IHC, IP, ICC, IF, AA 宿主: 小鼠 Monoclonal N23b-49 (Formerly S23b-49) Atto 488
anti-SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2) (AA 84-309) antibody (Atto 390)SHANK2 适用: 大鼠 WB, IHC, IP, ICC, IF, AA 宿主: 小鼠 Monoclonal N23b-49 (Formerly S23b-49) Atto 390
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- SHANK2 (SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2))
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别名
- SHANK2
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背景
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Synonyms: Cortactin binding protein 1, Cortactin SH3 domain-binding protein, Cortactin-binding protein 1, CortBP1, CTTNBP1, GKAP/SAPAP interacting protein, GKAP/SAPAP-interacting protein, KIAA1022, Proline rich synapse associated protein 1, Proline-rich synapse-associated protein 1, PROSAP1, SH3 and multiple ankyrin repeat domains protein 2, SHANK, Shank2, Shank2, SPANK3, SPANK-3, SHAN2_HUMAN.
Background: SH3 and multiple ankyrin repeat domains 1-3 (Shank1-3) of the Shank/ProSAP family are molecular scaffolds in the postsynaptic density (PSD). The PSD is an electron-dense structure underneath the postsynaptic plasma membrane of excitatory synapses that anchors and clusters glutamate receptors opposite to the presynaptic neurotransmitter release site. Shank proteins contain PDZ modular domains that coordinate the synaptic localization of ion channels, receptors, signaling enzymes, and cell adhesion molecules. The PDZ domain mediates protein-protein interactions via the recognition of a conserved sequence motif at the C-terminus of their target protein(s). Shank recruits betaPIX and PAK to spines to regulate postsynaptic structure and interacts with NMDA receptor and metabotropic glutamate receptor complexes. Transcript splice variation in the Shank family influences the spectrum of Shank-interacting proteins in the PSDs of adult and developing brain to ensure normal development.
抗原
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