TCF12 抗体 (AA 51-150) (Cy7)
Quick Overview for TCF12 抗体 (AA 51-150) (Cy7) (ABIN1407978)
抗原
See all TCF12 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 51-150
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交叉反应
- 人, 大鼠
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预测反应
- Mouse,Sheep,Horse,Rabbit,Zebrafish
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human TCF12
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亚型
- IgG
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- TCF12 (Transcription Factor 12 (TCF12))
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别名
- TCF12/HEB
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背景
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Synonyms: bHLHb20, Class B basic helix-loop-helix protein 20, DNA binding protein HTF4, DNA-binding protein HTF4, E box binding protein, E-box-binding protein, HEB, HTF4, HTF4_HUMAN, TCF-12, Tcf12, Transcription factor 12, Transcription factor HTF-4, Transcription factor HTF4.
Background: Differentiation of myogenic cells is regulated by multiple positively and negatively acting factors. One well characterized family of helix-loop-helix (HLH) proteins known to play an important role in the regulation of muscle cell development includes Myo D, myogenin, Myf-5 and Myf-6 (also designated MRF-4 or herculin). Myo D transcription factors form heterodimers with products of a more widely expressed family of bHLH genes, the E family, which consists of at least three distinct genes: E2A, IF2 and HEB. Myo D-E heterodimers bind avidly to consensus (CANNTG) E box target sites that are functionally important elements in the upstream regulatory sequences of many muscle-specific terminal differentiation genes. Both homo- and hetero-oligomers of these proteins are able to distinguish very closely related E box proteins and are believed to play important roles in lineage specific gene expression.
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基因ID
- 6938
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UniProt
- Q99081
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途径
- SARS-CoV-2 Protein Interactome
抗原
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