XPO5 抗体 (AA 221-320) (Cy7)
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北京 101111
Quick Overview for XPO5 抗体 (AA 221-320) (Cy7) (ABIN1407870)
抗原
See all XPO5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 221-320
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交叉反应
- 小鼠
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预测反应
- Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Exportin 5
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亚型
- IgG
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anti-Exportin 5 (XPO5) (AA 1-280) antibody
XPO5 适用: 人 WB, IF, ELISA, IP 宿主: 小鼠 Monoclonal 2C5-1B3 unconjugated
anti-Exportin 5 (XPO5) (AA 925-1204) antibodyXPO5 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Exportin 5 (XPO5) (AA 1-1204) antibodyXPO5 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Exportin 5 (XPO5) (AA 1-1204) antibodyXPO5 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Exportin 5 (XPO5) antibodyXPO5 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB2610 unconjugated Recombinant Antibody
anti-Exportin 5 (XPO5) antibodyXPO5 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Exportin 5 (XPO5) (AA 1115-1164) antibodyXPO5 适用: 人, 小鼠, 大鼠, 豚鼠, 马, 兔, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Exportin 5 (XPO5) (AA 190-239) antibodyXPO5 适用: 人, 小鼠, 大鼠, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-Exportin 5 (XPO5) (AA 182-231) antibodyXPO5 适用: 人, 小鼠, 大鼠, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Exportin 5 (XPO5) (N-Term) antibodyXPO5 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- XPO5 (Exportin 5 (XPO5))
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别名
- Exportin 5
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背景
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Synonyms: Exp 5, Exp5, Exportin 5, Exportin-5, Exportin5, FLJ14239, FLJ32057, FLJ45606, KIAA1291, Ran binding protein 21, Ran-binding protein 21, Ranbp 21, Ranbp21, Xpo 5, xpo5, XPO5_HUMAN.
Background: Exportin 5 (XPO5) is a member of the importin _ family of proteins and functions in tRNA export in a sequence dependent fashion. More recently, it has been shown to export pre-miRNA by a RanGTPase-driven process from the nucleus to the cytoplasm, where pre-miRNA processing occurs to produce mature miRNAs. Study of the miRNA biosynthesis pathway is essential in understanding the process of oncogenesis as global downregulation of miRNAs and the resulting alterations in the expression of tumor suppressor and oncogenic proteins is a common phenotype of cancers cells . Research studies have shown disruption of exportin 5 functions in many types of cancers including breast and lung, where pre-miRNA accumulates in the nucleus and miRNA maturation is impaired.
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途径
- Regulatory RNA Pathways, Protein targeting to Nucleus
抗原
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