Acl6b/Baf53b (AA 301-400) 抗体 (Cy7)
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北京 101111
Quick Overview for Acl6b/Baf53b (AA 301-400) 抗体 (Cy7) (ABIN1407732)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 301-400
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预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human ACL6B
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亚型
- IgG
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- Acl6b/Baf53b
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背景
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Synonyms: 53 kDa BRG1 associated factor B, ACL 6B, ACL6B, Actin like 6, Actin like protein 6B, Actin like protein6B, Actin related protein, Actin related protein Baf53b, actin-like 6B, Actl 6, ACTL 6B, Actl6, ACTL6 B, ACTL6B, Arp Na, ArpN a, ArpN alpha, ArpNa, ArpNalpha, Baf 53b, ACL6B_HUMAN.
Background: BAF53b is a member of a family of actin-related proteins (ARPs), which shares significant sequence identity with conventional actins. Both actins and ARPs comprise an actin fold, which forms an ATP binding cleft. BAF53b is a component of the BAF (BRG/brm-associated factor) complex in mammals, which is functionally related to the SWI/SNF complex in S. cerevisiae and Drosophila, and is associated with chromatin remodelling to facilitate transcriptional activation. As neural progenitors exit the cell cycle, the highly homologous BAF53a subunit of the BAF complex is replaced by BAF53b. This subunit switch is essential for the transition from from neural stem cells / progenitors to postmitotic neurons. BAF53b also plays a role in dendritic outgrowth, during which it is required to recruit the BAF complex and the dendritic regulator CREST to specific gene promoters. This function can not be performed by BAF53a.
抗原
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