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Junctophilin 3 抗体 (AA 181-280) (Cy7)

This Cy7-conjugated 兔 多克隆 anti-Junctophilin 3 antibody specifically detects Junctophilin 3 in WB, IF (cc) 和 IF (p). The antibody is reactive with 人 samples.
产品编号 ABIN1407060
发货至: 中国
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Quick Overview for Junctophilin 3 抗体 (AA 181-280) (Cy7) (ABIN1407060)

抗原

See all Junctophilin 3 (JPH3) 抗体
Junctophilin 3 (JPH3)

适用

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宿主

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克隆类型

  • 34
多克隆

标记

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This Junctophilin 3 antibody is conjugated to Cy7

应用范围

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Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

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    AA 181-280

    预测反应

    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Zebrafish

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Junctophilin 3

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    Junctophilin 3 (JPH3)

    别名

    Junctophilin 3

    背景

    Synonyms: JP-3, JP3, JPH3, JPH3_HUMAN, Junctophilin3, Junctophilin type 3, Junctophilin-3, TNRC22, Trinucleotide repeat-containing gene 22 protein.

    Background: Junctophilins are components of the junctional complexes between plasma membranes and endoplasmic or sarcoplasmic reticulums present in all excitable cells. Junctophilins contain a cytoplasmic domain which binds to the plasma membrane, as well as an ER/SR membrane spanning hydrophobic C-terminal segment. The three subtypes in this family are Junctophilin-1, -2 and -3. Junctophilin-1 is predominantly expressed in skeletal muscle, but is also expressed at low levels in heart. Junctophilin-2 is expressed in heart and skeletal muscle. Mutant mice lacking the Jph2 gene exhibit embryonic lethality and possess cardiac myocytes that express abnormal calcium transients. Junctophilin-3 is expressed in brain. The JPH3 alternatively spliced exon 2A has been suggested as a site for CTG repeat expansion leading to a Huntington disease-like autosomal dominant disorder.

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