FAT3 抗体 (AA 601-800) (Cy7)
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北京 101111
Quick Overview for FAT3 抗体 (AA 601-800) (Cy7) (ABIN1407048)
抗原
See all FAT3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 601-800
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预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human CDHF15/FAT3
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亚型
- IgG
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anti-FAT Tumor Suppressor Homolog 3 (FAT3) (AA 1209-1470) antibody
FAT3 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- FAT3 (FAT Tumor Suppressor Homolog 3 (FAT3))
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别名
- CDHF15/FAT3
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背景
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Synonyms: Cadherin family member 15, CDHF15, CDHR10, FAT tumor suppressor homolog 3, Fat3, FAT3_HUMAN, hFat3, Protocadherin Fat 3.
Background: The cadherins represent a family of Ca2+-dependent adhesion molecules that function to mediate cell to cell binding that is critical for the maintenance of structure and morphogenesis. Cadherins each contain a large extracellular domain at the N-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short C-terminal intracellular domain interacts with a variety of cytoplasmic proteins, including -catenin, to regulate cadherin function. The cadherin superfamily includes cadherins, protocadherins, desmogleins and desmocollins. FAT3 (FAT tumor suppressor homolog 3, also known as CDHF15 or CDHR10, is a 4,589 amino acid single-pass type I membrane protein expressed in ES cells, primitive neuroectoderm, fetal brain, infant brain, adult neural tissues and prostate. Containing thirty-three cadherin domains, four EGF-like domains and one laminin G-like domain, FAT3 may participate in the interactions between neurites derived from specific subsets of neurons during development.
抗原
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