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Netrin 4 抗体 (AA 520-628) (Cy5)

This anti-Netrin 4 antibody is a 兔 多克隆 antibody detecting Netrin 4 in WB, IF (cc) 和 IF (p). Suitable for 人.
产品编号 ABIN1406326
发货至: 中国

Quick Overview for Netrin 4 抗体 (AA 520-628) (Cy5) (ABIN1406326)

抗原

See all Netrin 4 (NTN4) 抗体
Netrin 4 (NTN4)

适用

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  • 2
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  • 1
  • 1
  • 1

宿主

  • 24
  • 4
  • 1

克隆类型

  • 25
  • 4
多克隆

标记

  • 16
  • 1
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This Netrin 4 antibody is conjugated to Cy5

应用范围

  • 27
  • 13
  • 13
  • 8
  • 7
  • 4
  • 4
  • 4
  • 4
  • 1
Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 520-628

    预测反应

    Human,Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Netrin 4

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    Netrin 4 (NTN4)

    别名

    Netrin 4

    背景

    Synonyms: Beta netrin, Beta-netrin, Hepar derived netrin like protein, Hepar-derived netrin-like protein, NET4_HUMAN, Netrin-4, Netrin4, NTN 4, NTN4.

    Background: Netrin proteins are a family of laminin-related secreted proteins that provide guidance signals for axonal growth and cell migration during development. Netrin signaling is dependent on the concentration of calcium outside the cell and the level of PKA activity. In axonal cells, a reduction in PKA activity converts the responsiveness of the axons to the netrin proteins, as the cells are repelled, rather than attracted, by the netrin gradient. Netrin-4 is related to the Laminin chains, and is therefore also designated -netrin. It is present in the basement membranes of the vasculature, lateral olfactory tract, kidney and ovary. In humans, the gene encoding for the netrin-4 protein is localized to chromosome 12q22-q23. High levels of netrin-4 mRNA have also been detected in many cells and tissues, including cerebral cortex, hippocampus, amygdaloid nuclei and Purkinje cells. Netrin-4 is important in neural, kidney and vascular development.

    基因ID

    59277
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