C11orf24 抗体 (FITC)
Quick Overview for C11orf24 抗体 (FITC) (ABIN1405550)
抗原
适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human C11orf24
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亚型
- IgG
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anti-Chromosome 11 Open Reading Frame 24 (C11orf24) (AA 61-110) antibody
C11orf24 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Chromosome 11 Open Reading Frame 24 (C11orf24) (N-Term) antibodyC11orf24 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- IF(IHC-P) 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- C11orf24 (Chromosome 11 Open Reading Frame 24 (C11orf24))
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别名
- C11orf24
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背景
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Synonyms: CK024_HUMAN, Protein DM4E3, Uncharacterized protein C11orf24.
Background: C11orf24, also known as DM4E3, is a 449 amino acid single-pass type I membrane protein that is expressed in brain, lung, skeletal muscle, kidney, spleen, prostate, testis, ovary and small intestine, with highest expression in heart, placenta, liver, pancreas and colon, and low expression in thymus and leukocytes. C11orf24 is encoded by a gene located on human chromosome 11, which consists of approximately 135 million base pairs and 1,400 genes. Chromosome 11 makes up around 4 % of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and _ thalassemia are caused by HBB gene mutations. Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11.
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基因ID
- 53838
抗原
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