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SRI 抗体 (AbBy Fluor® 647)

This anti-SRI antibody is a 兔 多克隆 antibody detecting SRI in WB 和 IF (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN1405152
发货至: 中国

Quick Overview for SRI 抗体 (AbBy Fluor® 647) (ABIN1405152)

抗原

See all SRI 抗体
SRI (Sorcin (SRI))

适用

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  • 23
  • 4
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  • 4
  • 3
  • 3
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  • 2
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人, 小鼠, 大鼠

宿主

  • 46
  • 5

克隆类型

  • 46
  • 5
多克隆

标记

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  • 3
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  • 3
  • 1
  • 1
  • 1
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  • 1
  • 1
  • 1
  • 1
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  • 1
  • 1
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This SRI antibody is conjugated to AbBy Fluor® 647

应用范围

  • 37
  • 16
  • 12
  • 12
  • 7
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  • 4
  • 4
  • 2
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human SR1/Sorcin

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    SRI (Sorcin (SRI))

    别名

    Sorcin

    背景

    Synonyms: 22 kDa protein, Calcium binding protein amplied in mutlidrug resistant cells, CP 22, CP-22, CP22, SCN, Sorcin class 4 gene, Sorcin, SORCN_HUMAN, SRI, V19.

    Background: Sorcin is a highly conserved protein, with 95 % homology between hamster and human sorcin sequences. Sorcin has four putative Ca-binding domains, two of which exhibit strong homology to calmodulin EF hand? motifs. Calcium binding directly to sorcin has been demonstrated by in vitro assays. Sorcin is closely related to members of calpain and sarcoplasmic Ca2+-binding protein subfamilies. Sorcin undergoes calcium-dependent translocation from the cytosol to cellular membranes. Sorcin binds to and modulates ryanodine receptors and is widely distributed including heart and brain tissues. At the subcellular level, sorcin localizes to T-tubule junctions of cardiac sarcoplasmic reticulum.

    基因ID

    6717

    途径

    Transition Metal Ion Homeostasis, Maintenance of Protein Location, Negative Regulation of Transporter Activity
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