MYBPC3 抗体 (AbBy Fluor® 647)
Quick Overview for MYBPC3 抗体 (AbBy Fluor® 647) (ABIN1405134)
抗原
See all MYBPC3 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human MYBPC3
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亚型
- IgG
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anti-Myosin Binding Protein C, Cardiac (MYBPC3) (AA 1070-1123) antibody
MYBPC3 适用: 人, 大鼠, 小鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Myosin Binding Protein C, Cardiac (MYBPC3) (AA 200-400) antibodyMYBPC3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Myosin Binding Protein C, Cardiac (MYBPC3) antibodyMYBPC3 适用: 大鼠, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Myosin Binding Protein C, Cardiac (MYBPC3) (AA 189-218), (N-Term) antibodyMYBPC3 适用: 人, 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB31023 unconjugated
anti-Myosin Binding Protein C, Cardiac (MYBPC3) (AA 1-328) antibodyMYBPC3 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Myosin Binding Protein C, Cardiac (MYBPC3) (C-Term) antibodyMYBPC3 适用: 人 ELISA, WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Myosin Binding Protein C, Cardiac (MYBPC3) (AA 188-218), (N-Term) antibodyMYBPC3 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- IF(IHC-P) 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- MYBPC3 (Myosin Binding Protein C, Cardiac (MYBPC3))
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别名
- MYBPC3
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背景
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Synonyms: C protein cardiac muscle isoform, cardiac muscle isoform, cardiac-type, C-protein, Cardiac MyBP C, Cardiac MyBP-C, Cardiac myosin binding protein C, MYBP C, MYBPC, MYBPC3, Myosin binding protein C cardiac, Myosin binding protein C cardiac-type, Myosin-binding protein C, MYPC3_HUMAN.
Background: MYBPC3 encodes the cardiac isoform of the thick-filament myosin-binding protein C. It is found in the crossbridge-bearing zone (C region) of A bands in vertebrate striated muscle. Regulatory phosphorylation of MYBPC3 by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. MYBPC3 binds F-Actin, MHC and native thin filaments, and modifies the activity of Actin-activated myosin ATPase. Mutations in the MYBPC3 gene lead mainly to truncation of the protein, which results in one cause of familial hypertrophic cardiomyopathy type 4 (CMH4), a heart disorder characterized by ventricular hypertrophy, which often involves the interventricular septum and is usually asymmetric. The MYBPC3 gene maps to chromosome 11p11.2.
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基因ID
- 4607
抗原
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