INTS3 抗体 (AA 960-998) (FITC)
Quick Overview for INTS3 抗体 (AA 960-998) (FITC) (ABIN1404542)
抗原
See all INTS3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 960-998
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human INTS3
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亚型
- IgG
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anti-Integrator Complex Subunit 3 (INTS3) (AA 518-551) antibody
INTS3 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB56744 unconjugated
anti-Integrator Complex Subunit 3 (INTS3) (AA 960-998) antibodyINTS3 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Integrator Complex Subunit 3 (INTS3) (AA 901-1043) antibodyINTS3 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Integrator Complex Subunit 3 (INTS3) (AA 1000-1034) antibodyINTS3 适用: 人 WB 宿主: 兔 Polyclonal RB56745 unconjugated
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应用备注
- IF(IHC-P) 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- INTS3 (Integrator Complex Subunit 3 (INTS3))
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别名
- INTS3
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背景
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Synonyms: INT3, SOSSA, SOSS-A, C1orf60, C1orf193, Integrator complex subunit 3, SOSS complex subunit A, Sensor of single-strand DNA complex subunit A, Sensor of ssDNA subunit A, INTS3
Background: Component of the Integrator complex. The Integrator complex is involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. The SOSS complex is required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways. In the SOSS complex, it is required for the assembly of the complex and for stabilization of the complex at DNA damage sites.
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基因ID
- 65123
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UniProt
- Q68E01
抗原
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