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B-Cell Linker 抗体 (pTyr189) (Biotin)

Name: B-Cell Linker 抗体 (pTyr189) (Biotin)
SKU: ABIN1404097
Availability: OutOfStock

This anti-B-Cell Linker antibody is a 兔多克隆 antibody detecting B-Cell Linker in WB 和 IHC (p). Suitable for 人, 小鼠和大鼠.

产品编号 ABIN1404097

发货至: 中国

Quick Overview for B-Cell Linker 抗体 (pTyr189) (Biotin) (ABIN1404097)

抗原

See all B-Cell Linker (BLNK) 抗体

B-Cell Linker (BLNK)

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This B-Cell Linker antibody is conjugated to Biotin

应用范围

Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Discover our top product BLNK Primary Antibody

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pTyr189

交叉反应

人, 小鼠, 大鼠

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic phosphopeptide derived from human BLNK around the phosphorylation site of Tyr189 [EN(p-Y)IH]

亚型

IgG
anti-B-Cell Linker (BLNK) antibody
BLNK 适用: 人, 小鼠 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 5G9 unconjugated

anti-B-Cell Linker (BLNK) (AA 65-314) antibody
BLNK 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-B-Cell Linker (BLNK) (C-Term) antibody
Verified BLNK 适用: 人 WB, ELISA, FACS, IF 宿主: 山羊 Polyclonal unconjugated

anti-B-Cell Linker (BLNK) (AA 301-400) antibody
BLNK 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 1D7 unconjugated

anti-B-Cell Linker (BLNK) (pTyr96) antibody
BLNK 适用: 人 WB, ELISA, IF (p), IHC (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-B-Cell Linker (BLNK) (AA 41-337) antibody
BLNK 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-B-Cell Linker (BLNK) (N-Term) antibody
BLNK 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-B-Cell Linker (BLNK) (pTyr96) antibody
BLNK 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-B-Cell Linker (BLNK) (pTyr84) antibody
BLNK 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-B-Cell Linker (BLNK) antibody
BLNK 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:300-5000
IHC-P 1:200-400

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20°C for 12 months.

有效期

12 months
抗原

B-Cell Linker (BLNK)

别名

BLNK

背景

Synonyms: BLNK phospho Y491, p-BLNK phospho Y491, B cell adapter containing SH2 domain protein, B cell adapter containing Src homology 2 domain protein, B cell linker, B cell linker protein, B cell linker protein, B-cell adapter containing a SH2 domain protein, B-cell adapter containing a Src homology 2 domain protein, B-cell linker protein, BASH, BASH, Bca, Bca, BLNK, BLNK s, BLNK_HUMAN, Cytoplasmic adapter protein, Ly 57, Ly-57, Ly57, Lymphocyte antigen 57, Lymphocyte antigen-57, Lyw 57, Lyw-57, Lyw57, MGC111051, SLP 65, SLP65, SLP-65, Src homology 2 domain containing leukocyte protein of 65 kDa.
Background: This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012].

基因ID

29760

途径

BCR Signaling