C17orf49 抗体 (Biotin)
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- 抗原 See all C17orf49 抗体
- C17orf49 (Chromosome 17 Open Reading Frame 49 (C17orf49))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This C17orf49 antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human C17orf49
- 亚型
- IgG
- Top Product
- Discover our top product C17orf49 Primary Antibody
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anti-Chromosome 17 Open Reading Frame 49 (C17orf49) (C-Term) antibody
C17orf49 适用: 人, 小鼠, 大鼠, 马, 犬, 豚鼠, Cow, 斑马鱼, Pig, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Chromosome 17 Open Reading Frame 49 (C17orf49) (AA 1-172) antibodyC17orf49 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- C17orf49 (Chromosome 17 Open Reading Frame 49 (C17orf49))
- 别名
- C17orf49 (C17orf49 产品)
- 别名
- BAP18 antibody, HEPIS antibody, bap18 antibody, C17orf49 antibody, MGC145240 antibody, 1110020A23Rik antibody, AL033328 antibody, AU045833 antibody, Bap18 antibody, RP23-198E14.7 antibody, chromosome 17 open reading frame 49 antibody, chromosome 17 open reading frame 49 S homeolog antibody, chromosome 19 open reading frame, human C17orf49 antibody, chromosome 16 open reading frame, human C17orf49 antibody, RIKEN cDNA 0610010K14 gene antibody, similar to RIKEN cDNA 1110020A23 antibody, C17orf49 antibody, c17orf49.S antibody, C19H17orf49 antibody, C16H17orf49 antibody, c17orf49 antibody, 0610010K14Rik antibody, RGD1308134 antibody
- 背景
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Synonyms: Bap18, BAP18_HUMAN, BPTF-associated protein of 18 kDa, Chromatin complexes subunit BAP18, Chromosome 17 open reading frame 49, Hypothetical protein LOC124944, MGC49942, Uncharacterized potential DNA binding protein C17orf49.
Background: C17orf49 is a 172 amino acid protein that is encoded by a gene mapping to human chromosome 17. Chromosome 17 makes up over 2.5 % of the human genome with about 81 million bases encoding over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. Chromosome 17 is also linked to neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17.
- 基因ID
- 124944
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