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PIBF1 抗体 (Biotin)

This anti-PIBF1 antibody is a 兔 多克隆 antibody detecting PIBF1 in WB 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN1403647
发货至: 中国

Quick Overview for PIBF1 抗体 (Biotin) (ABIN1403647)

抗原

See all PIBF1 抗体
PIBF1 (Progesterone Immunomodulatory Binding Factor 1 (PIBF1))

适用

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人, 小鼠, 大鼠

宿主

  • 53
  • 6

克隆类型

  • 55
  • 4
多克隆

标记

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  • 1
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This PIBF1 antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human PIBF1/C13orf24

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    PIBF1 (Progesterone Immunomodulatory Binding Factor 1 (PIBF1))

    别名

    PIBF1

    背景

    Synonyms: PIBF 1, PIBF, PIBF1, PIBF-1, Progesterone immunomodulatory binding factor 1, Progesterone induced blocking factor 1, Progesterone-Induced Blocking Factor 1, RP11 505F3.1, PIBF1_HUMAN, C13orf24.

    Background: PIBF is synthesized during pregnancy in response to progesterone by progesterone receptor-positive T lymphocytes (mostly gamma-delta T cells). In the presence of PIBF, natural killer (NK) cells inhibit the release of perforin from storage granules and therefore fail to lyse target cells. In humans, the amount of cells that express PIBF is significantly higher in healthy pregnant women than in women at risk for premature pregnancy termination. Full-length PIBF is associated with the nucleus, whereas secretion of shorter forms is induced by activation of the cell. Research suggests that PIBF functions as a transcription factor in its full-length form, while smaller forms may act as cytokines. The PIBF gene encodes a deduced hydrophilic 757-amino acid alpha-helical protein with an N-terminal signal sequence, a leucine zipper motif, a basic zipper sequence, a PEST sequence, a nuclear localization signal, an endoplasmic reticulum membrane retention signal, and many presumeed N-glycosylation and phosphorylation sites.

    基因ID

    10464
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