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TCF25 抗体 (AbBy Fluor® 555)

This anti-TCF25 antibody (ABIN1403597) is a Rabbit Polyclonal antibody detecting TCF25 in WB, IF (p). Suitable for Human, Mouse, Rat.
产品编号 ABIN1403597
发货至: 中国

Quick Overview for TCF25 抗体 (AbBy Fluor® 555) (ABIN1403597)

抗原

See all TCF25 抗体
TCF25 (Transcription Factor 25 (Basic Helix-Loop-Helix) (TCF25))

适用

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人, 小鼠, 大鼠

宿主

  • 46
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克隆类型

  • 47
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多克隆

标记

  • 25
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This TCF25 antibody is conjugated to AbBy Fluor® 555

应用范围

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Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Transcription factor 25

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    TCF25 (Transcription Factor 25 (Basic Helix-Loop-Helix) (TCF25))

    别名

    Transcription factor 25

    背景

    Synonyms: FKSG26, hKIAA1049, NULP1, PRO2620, Hulp1, KIAA1049, Nuclear localized protein 1, Transcription factor 25 basic helix loop helix, TCF25_HUMAN.

    Background: Transcription factor 25 acts as a transcriptional repressor. It has been shown to repress transcription of SRF in vitro and hence may play a role in heart development.Transcription factor 25, is a 676 amino acid protein that plays a role in cell death. A member of the TCF25 family, Nulp1 utilizes its C-terminus to mediate transcriptional repression of SRF in vitro, and interacts with XIAP. Nulp1 localizes primarily to the nucleus but is also found in cytosol. Widely expressed, Nulp1 is found at high levels in embryonic brain and adult heart. The gene encoding Nulp1 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3 % of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.

    基因ID

    22980
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