ALAS1 抗体 (AbBy Fluor® 488)
Quick Overview for ALAS1 抗体 (AbBy Fluor® 488) (ABIN1403242)
抗原
See all ALAS1 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human ALAS1/ALAS-H
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亚型
- IgG
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anti-Aminolevulinate, delta-, Synthase 1 (ALAS1) (AA 1-98) antibody
ALAS1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3G10 unconjugated
anti-Aminolevulinate, delta-, Synthase 1 (ALAS1) antibodyALAS1 适用: 人, 小鼠 WB, IF (cc) 宿主: 兔 Monoclonal 1G11 unconjugated
anti-Aminolevulinate, delta-, Synthase 1 (ALAS1) (AA 57-285) antibodyALAS1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Aminolevulinate, delta-, Synthase 1 (ALAS1) (Internal Region) antibodyALAS1 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Aminolevulinate, delta-, Synthase 1 (ALAS1) antibodyALAS1 适用: 人 WB, ELISA 宿主: 兔 Monoclonal 2A9 unconjugated Recombinant Antibody
anti-Aminolevulinate, delta-, Synthase 1 (ALAS1) (AA 146-195) antibodyALAS1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Aminolevulinate, delta-, Synthase 1 (ALAS1) antibodyALAS1 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Aminolevulinate, delta-, Synthase 1 (ALAS1) (AA 1-250) antibodyALAS1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Aminolevulinate, delta-, Synthase 1 (ALAS1) (N-Term) antibodyALAS1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Aminolevulinate, delta-, Synthase 1 (ALAS1) antibodyKD Validated ALAS1 适用: 人 WB, IF, ICC 宿主: 兔 Monoclonal unconjugated Recombinant Antibody
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应用备注
- IF(IHC-P) 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- ALAS1 (Aminolevulinate, delta-, Synthase 1 (ALAS1))
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别名
- ALAS1
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背景
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Synonyms: mitochondrial, nonspecic, 5 aminolevulinate synthase, 5 aminolevulinate synthase nonspecic mitochondrial, 5 aminolevulinic acid synthase, 5-aminolevulinate synthase, 5-aminolevulinic acid synthase 1, Alas 1, ALAS 3, ALAS, ALAS H, ALAS N, ALAS-H, alaS1, ALAS3, ALASH, Aminolevulinate delta synthase 1, Aminolevulinic acid synthase 1, Delta ALA synthetase, Delta aminolevulinate synthase, Delta-ALA synthase 1, Delta-aminolevulinate synthase 1, HEM1_HUMAN, MIG 4, MIG4, Migration inducing protein 4.
Background: 5-aminolevulinate synthase 1 (ALAS-H) and 2 (ALAS-E) are two isoforms of ALAS, an enzyme catalyzing the first step of the heme biosynthetic pathway in mammals. The erythroid-specific isoenzyme, ALAS-E, regulates the first step of hematopoietic cell differentation and iron metabolism in the liver. ALAS-H is a housekeeping protein which mediates synthesis of early heme in the mitochondria of most cells. Succinyl CoA associates with ALAS-E in protein conformation change and translocation of ALAS-E into the mitochondria and does not interact with ALAS-H. The ALAS-E 5'-flanking region contains binding sites for nuclear activators such as GATA-1, NF-E2 and EKLF. Since the ALAS gene maps to the X chromosome, mutation of the gene leads to the pyridoxine-refractory X-linked sideroblastic anemia.
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基因ID
- 211
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途径
- Regulation of Lipid Metabolism by PPARalpha
抗原
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