ZFPM1 抗体 (Biotin)
Quick Overview for ZFPM1 抗体 (Biotin) (ABIN1402789)
抗原
See all ZFPM1 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
 - 人, 小鼠, 大鼠
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纯化方法
 - Purified by Protein A.
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免疫原
 - KLH conjugated synthetic peptide derived from human FOG1
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亚型
 - IgG
 
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应用备注
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                        WB 1:300-5000
IHC-P 1:200-400 - 
                                            
限制
 - 仅限研究用
 
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状态
 - Liquid
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浓度
 - 1 μg/μL
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缓冲液
 - Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
 - ProClin
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注意事项
 - This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
 - -20 °C
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储存方法
 - Store at -20°C for 12 months.
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有效期
 - 12 months
 
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- ZFPM1 (Zinc Finger Protein, Multitype 1 (ZFPM1))
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别名
 - FOG1
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背景
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Synonyms: FOG-1, FOG1_HUMAN, Friend of GATA 1, Friend of GATA protein 1, Friend of GATA1, ZFPM1, Zinc finger protein, Zinc finger protein 89A, Zinc finger protein multitype 1, Zinc finger protein ZFPM1.
Background: Transcription regulator that plays an essential role in erythroid and megakaryocytic cell differentiation. Essential cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family GATA1, GATA2 and GATA3. Such heterodimer can both activate or repress transcriptional activity, depending on the cell and promoter context. The heterodimer formed with GATA proteins is essential to activate expression of genes such as NFE2, ITGA2B, alpha- and beta-globin, while it represses expression of KLF1. May be involved in regulation of some genes in gonads. May also be involved in cardiac development, in a non-redundant way with ZFPM2/FOG2.
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基因ID
 - 161882
 
抗原
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