TAL1 抗体 (AbBy Fluor® 488)
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北京 101111
Quick Overview for TAL1 抗体 (AbBy Fluor® 488) (ABIN1402654)
抗原
See all TAL1 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Tal1
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亚型
- IgG
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anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) (C-Term) antibody
TAL1 适用: 人, 犬, Cow, 豚鼠, 马, 兔, Pig, 猴, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) (C-Term) antibodyTAL1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) antibodyTAL1 适用: 人 WB, FACS, IF 宿主: 小鼠 Monoclonal 4G10 unconjugated
anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) (AA 1-114) antibodyTAL1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) (AA 154-188) antibodyTAL1 适用: 人 WB 宿主: 兔 Polyclonal RB50954 unconjugated
anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) (C-Term) antibodyTAL1 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) antibodyTAL1 适用: 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) (AA 236-285) antibodyTAL1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, Pig, 猴, Bat, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) (N-Term) antibodyTAL1 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- IF(IHC-P) 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- TAL1 (T-Cell Acute Lymphocytic Leukemia 1 (TAL1))
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别名
- Tal1
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背景
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Synonyms: bHLHa17, Class A basic helix-loop-helix protein 17, SCL antibody, Stem cell protein, T cell acute lymphocytic leukemia 1, T cell acute lymphocytic leukemia 1 protein, T cell leukemia/lymphoma 5 protein, T-cell acute lymphocytic leukemia protein 1, T-cell leukemia/lymphoma protein 5, Tal 1, Tal 1 product, TAL 1 protein, TAL-1, tal1, TAL1_HUMAN, TCL 5, TCL5.
Background: Activation of TAL1 characterizes up to 60 % of cases of human T cell acute lymphoblastic leukemia, making it the most frequent gain-of-function mutation observed in this disorder. TAL1 (also designated SCL) is a serine phosphoprotein and basic helix-loop-helix transcription factor known to regulate embryonic hematopoiesis. This transcription factor binds as a heterodimer with E2A and HEB/HTF4 to a nucleotide sequence motif termed the E-box. In addition, leukemogenesis is accelerated dramatically by transgenic co-expression of TAL1 and the catalytic subunit of casein kinase IIalpha, a serine/ threonine protein kinase known to modulate the activity of other bHLH transcription factors.
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途径
- Stem Cell Maintenance
抗原
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