LRSAM1 抗体 (Biotin)
Quick Overview for LRSAM1 抗体 (Biotin) (ABIN1402417)
抗原
See all LRSAM1 抗体适用
宿主
克隆类型
标记
应用范围
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    - 
                                            交叉反应
- 人, 小鼠, 大鼠
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                                            纯化方法
- Purified by Protein A.
- 
                                            免疫原
- KLH conjugated synthetic peptide derived from human LRSAM1
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                                            亚型
- IgG
 
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                                            应用备注
- 
                        WB 1:300-5000
 IHC-P 1:200-400
- 
                                            限制
- 仅限研究用
 
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                                            状态
- Liquid
- 
                                            浓度
- 1 μg/μL
- 
                                            缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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                                            储存液
- ProClin
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                                            注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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                                            储存条件
- -20 °C
- 
                                            储存方法
- Store at -20°C for 12 months.
- 
                                            有效期
- 12 months
 
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    - LRSAM1 (Leucine Rich Repeat and Sterile alpha Motif Containing 1 (LRSAM1))
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                                            别名
- LRSAM1
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                                            背景
- 
                        Synonyms: E3 ubiquitin protein ligase LRSAM1, hTAL, Leucine rich repeat and sterile alpha mot containing protein 1, RLE, TAL, Tsg101 associated ligase, LRSM1_HUMAN. Background: LRSAM1 is an E3 ubiquitin-protein ligase that mediates monoubiquitination of TSG101 at multiple sites, leading to inactivation of the ability of TSG101 to sort endocytic (EGF receptors) and exocytic (HIV-1 viral proteins) cargos. It selectively regulates cell adhesion molecules and plays a role in receptor endocytosis and viral budding. LRSAM1 contains a RING-type zinc finger, 5 leucine-rich repeats and 1 SAM (sterile alpha motif) domain. The coiled coil domains interact with the SB domain of TSG101. The PTAP motifs mediate the binding to UEV domains. There are 3 isoforms produced by alternative splicing. 
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                                            基因ID
- 90678
 抗原
- 
                    
 
                                     
                                     
                                    