RNF125 抗体 (AbBy Fluor® 350)
Quick Overview for RNF125 抗体 (AbBy Fluor® 350) (ABIN1401717)
抗原
See all RNF125 抗体适用
宿主
克隆类型
标记
应用范围
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    - 
                                            交叉反应
- 人, 小鼠, 大鼠
- 
                                            纯化方法
- Purified by Protein A.
- 
                                            免疫原
- KLH conjugated synthetic peptide derived from human TRAC1/RNF125
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                                            亚型
- IgG
 
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    - 
                                            应用备注
- IF(IHC-P) 1:50-200
- 
                                            限制
- 仅限研究用
 
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    - 
                                            状态
- Liquid
- 
                                            浓度
- 1 μg/μL
- 
                                            缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 
                                            储存液
- ProClin
- 
                                            注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 
                                            储存条件
- -20 °C
- 
                                            储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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                                            有效期
- 12 months
 
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    - RNF125 (Ring Finger Protein 125 (RNF125))
- 
                                            别名
- RNF125
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                                            背景
- 
                        Synonyms: T cell RING activation protein 1, E3 ubiquitin protein ligase RNF125, Ring finger protein 125, RNF 125, T cell ring protein identied in activation screen, TRAC 1, TRAC1, RN125_HUMAN. Background: The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. TRAC-1 (T-cell RING activation protein 1), also known as RNF125 (ring finger protein 125) or E3 ubiquitin-protein ligase RNF125, is a 232 amino acid novel E3 ubiquitin ligase that functions as a positive regulator in the T-cell receptor signaling pathway. Expressed predominantly in lymphoid tissues such as spleen, thymus and bone marrow, TRAC-1 has been found to inhibit pathogen-induced cytokine production and down-regulates HIV replication. 
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                                            基因ID
- 9611
 抗原
- 
                    
 
                                     
                                     
                                    