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RNF125 抗体 (AbBy Fluor® 350)

This AbBy Fluor® 350-conjugated 兔 多克隆 anti-RNF125 antibody specifically detects RNF125 in WB 和 IF (p). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN1401717
发货至: 中国
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Quick Overview for RNF125 抗体 (AbBy Fluor® 350) (ABIN1401717)

抗原

See all RNF125 抗体
RNF125 (Ring Finger Protein 125 (RNF125))

适用

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人, 小鼠, 大鼠

宿主

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  • 3
  • 1

克隆类型

  • 30
  • 2
多克隆

标记

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This RNF125 antibody is conjugated to AbBy Fluor® 350

应用范围

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Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human TRAC1/RNF125

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    RNF125 (Ring Finger Protein 125 (RNF125))

    别名

    RNF125

    背景

    Synonyms: T cell RING activation protein 1, E3 ubiquitin protein ligase RNF125, Ring finger protein 125, RNF 125, T cell ring protein identied in activation screen, TRAC 1, TRAC1, RN125_HUMAN.

    Background: The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. TRAC-1 (T-cell RING activation protein 1), also known as RNF125 (ring finger protein 125) or E3 ubiquitin-protein ligase RNF125, is a 232 amino acid novel E3 ubiquitin ligase that functions as a positive regulator in the T-cell receptor signaling pathway. Expressed predominantly in lymphoid tissues such as spleen, thymus and bone marrow, TRAC-1 has been found to inhibit pathogen-induced cytokine production and down-regulates HIV replication.

    基因ID

    9611
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