SERPINB3 + SERPINB4 抗体 (AbBy Fluor® 488)
Quick Overview for SERPINB3 + SERPINB4 抗体 (AbBy Fluor® 488) (ABIN1401502)
抗原
适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human SERPINB3 (same as SERPINB4)
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亚型
- IgG
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应用备注
- IF(IHC-P) 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- SERPINB3 + SERPINB4
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背景
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Synonyms: HsT1196, Protein T4 A, Protein T4-A, SCC, SCCA PD, SCCA-1, SCCA1, SCCAPD, Serine or cysteine proteinase inhibitor clade B ovalbumin member 3, Serpin B3, Serpin peptidase inhibitor clade B ovalbumin member 3, SERPINB3, SPB3_HUMAN, Squamous cell carcinoma antigen 1, T4 A, T4A, SCCA 2, SCCA2, Leupin, Peptidase inhibitor 11, PI 11, PI-11, PI11, Protease inhibitor leucine serpin, SCCA-2, SCCA1, SCCA2/SCCA1 fusion protein, Serine or cysteine proteinase inhibitor, clade B ovalbumin, member 4, Serpin B4, Serpin peptidase inhibitor, clade B ovalbumin, member 4, SERPINB 4, SERPINB4, SPB4_HUMAN, Squamous cell carcinoma antigen 1, Squamous cell carcinoma antigen 2.
Background: Metastasis of a primary tumor to a distant site is determined through signaling cascades that break down interactions between the cell and extracellular matrix proteins. Among the proteins mediating metastasis are serine prote-ases, such as neutrophil elastase.SCCA is transcribed by two nearly identical genes (SCCA1 and SCCA2), and is mainly produced as SCCA1. The human SCCA1 gene encodes a 390 amino acid protein that was originally isolated from a metastatic cervical squamous cell carcinoma. SCCA2 may act as a protease inhibitor to modulate the host immune response against tumor cells.
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基因ID
- 6317
抗原
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