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SIP1 抗体 (AbBy Fluor® 647)

This anti-SIP1 antibody is a 兔 多克隆 antibody detecting SIP1 in IF (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN1401336
发货至: 中国

Quick Overview for SIP1 抗体 (AbBy Fluor® 647) (ABIN1401336)

抗原

See all SIP1 (GEMIN2) 抗体
SIP1 (GEMIN2) (Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This SIP1 antibody is conjugated to AbBy Fluor® 647

应用范围

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Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human SIP1

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    SIP1 (GEMIN2) (Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2))

    别名

    SIP1

    背景

    Synonyms: Smad Interacting Protein 1 SIP 1, SIP1 SIP-1, Smad-interacting protein 1, SMADIP 1, SMADIP1, ZEB 2, ZEB2, ZEB2_HUMAN, Zfhx1b, ZFHX1B protein, Zfx1b, Zinc finger E box binding protein 2, Zinc finger E-box-binding homeobox 2, Zinc finger homeobox 1b, zinc finger homeobox protein 1, Zinc finger homeobox protein 1b.

    Background: SMAD regulates gene expression by interacting with different classes of transcription factors including DNA-binding multi-zinc finger proteins. SIP1, for SMAD interacting protein 1, is a member of the delta-EF1/Zfh1 family of 2-handed zinc finger/homeodomain proteins. SIP1 contains a SMAD-binding domain, a homeodomain and two clusters of zinc fingers on the N- and C-termini. SIP1, also known as SMADIP1, ZFHX1B and ZEB2 (zinc finger E-box-binding protein 2), can be induced by TGF treatment. SIP1 plays a crucial role in normal embryonic development of neural structures and the neural crest. The human SIP1 gene maps to chromosome 2q22. Mutations in the SIP1 gene cause a form of Hirschsprung disease (HSCR). Patients with SIP1 mutations show mental retardation, delayed motor development, epilepsy, microcephaly, distinct facial features and/or congenital heart diseaseall symptoms of HSCR.

    基因ID

    9839

    途径

    Ribonucleoprotein Complex Subunit Organization, Tube Formation
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