TENM3 抗体 (Biotin)
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北京 101111
Quick Overview for TENM3 抗体 (Biotin) (ABIN1400611)
抗原
See all TENM3 (ODZ3) 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human ODZ3/Teneurin 3
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亚型
- IgG
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anti-Teneurin 3 (ODZ3) (Internal Region) antibody
Verified ODZ3 适用: 人 ELISA, IF 宿主: 山羊 Polyclonal unconjugated
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应用备注
- IHC-P 1:200-400
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- TENM3 (ODZ3) (Teneurin 3 (ODZ3))
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别名
- ODZ3
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背景
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Synonyms: ODZ3 like protein, Protein Odd Oz ten m homolog 3, Ten 3, Ten M3, Tenascin M3, Teneurin 3, Teneurin3, TNM3, FLJ10474, FLJ10886, KIAA1455, odd Oz Ten m homolog 3, odz odd Oz ten m homolog 3 Drosophila, odz odd Oz ten m homolog 3, TEN3_HUMAN.
Background: Teneurin-3, also known as Ten-3, TNM3 or ODZ3, is a 2,699 amino acid single-pass type II membrane protein that contains 25 YD repeats, 8 EGF-like domains, 5 NHL repeats and one teneurin N-terminal domain. Localized to the membrane and expressed in brain, testis and ovary, Teneurin-3 exists as a disulfide-liked homodimer that is thought to function as a cellular signal transducer. Additionally, Teneurin-3 may participate in eye-specific patterning in the visual pathway and is required for aligned binocular vision. The gene encoding Teneurin-3 maps to chromosome 4. Representing approximately 6 % of the human genome, chromosome 4 contains nearly 900 genes, one of which is the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease. FGFR-3 is also encoded on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer. Chromosome 4 is also tied to Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.
抗原
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