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PDZK1 抗体 (AbBy Fluor® 488)

This anti-PDZK1 antibody is a 兔 多克隆 antibody detecting PDZK1 in WB 和 IF (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN1400470
发货至: 中国

Quick Overview for PDZK1 抗体 (AbBy Fluor® 488) (ABIN1400470)

抗原

See all PDZK1 抗体
PDZK1 (PDZ Domain Containing 1 (PDZK1))

适用

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人, 小鼠, 大鼠

宿主

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  • 6
  • 1
  • 1

克隆类型

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多克隆

标记

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  • 1
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This PDZK1 antibody is conjugated to AbBy Fluor® 488

应用范围

  • 44
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Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human PDZK1

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    PDZK1 (PDZ Domain Containing 1 (PDZK1))

    别名

    PDZK1

    背景

    Synonyms: CAP70, CFTR associated protein of 70 kDa, CFTR associated protein, 70-KD, CFTR-associated protein of 70 kDa, CLAMP, D3Ertd537e, Dietary Pi-regulated RNA-1, Diphor-1, mPDZK1, Na+/H+ exchange regulatory cofactor NHE-RF3, Na+/H+ exchanger regulatory factor 3, Na/Pi cotransporter C-terminal-associated protein 1, Na/Pi cotransporter C-terminal-associated protein, NaPi Cap1, NaPi-Cap1, NaPiCap1, NHERF 3, NHERF-3, NHERF3, NHRF3_HUMAN, OTTHUMP00000015572, PDZ domain containing 1, PDZ domain containing protein 1, PDZ domain-containing protein 1, PDZD1, PDZK1, Sodium hydrogen exchanger regulatory factor 3, Sodium-hydrogen exchanger regulatory factor 3, 1700023D20Rik, 2610507N21Rik, 4921513F16Rik, AI267131, AI314638, AL022680, C terminal linking and modulating protein.

    Background: A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. May play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. May potentiate the CFTR chloride channel activity. May function to connect SCARB1 with the cellular machineries for intracellular cholesterol transport and/or metabolism. May be involved in the regulation of proximal tubular Na(+)-dependent inorganic phosphate cotransport therefore playing an important role in tubule function.

    基因ID

    5174
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