Eukaryotic Translation Initiation Factor 3, Subunit M (EIF3M) 抗体 (FITC)
Quick Overview for Eukaryotic Translation Initiation Factor 3, Subunit M (EIF3M) 抗体 (FITC) (ABIN1400456)
抗原
See all Eukaryotic Translation Initiation Factor 3, Subunit M (EIF3M) 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human PCID1
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亚型
- IgG
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应用备注
- IF(IHC-P) 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- Eukaryotic Translation Initiation Factor 3, Subunit M (EIF3M)
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别名
- PCID1
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物质类
- Viral Protein
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背景
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Synonyms: B5 receptor, Dendritic cell protein, e3m, E3M_HUMAN, Eukaryotic translation initiation factor 3 subunit M, Fetal lung protein B5, FLJ29030, GA17, hfl B5, hFL-B5, PCI domain containing 1 herpesvirus entry mediator, PCI domain-containing protein 1, PCID1.
Background: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. May favor virus entry in case of infection with herpes simplex virus 1 (HSV1) or herpes simplex virus 2 (HSV2).
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基因ID
- 10480
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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