MEPE 抗体 (AA 201-300) (AbBy Fluor® 488)
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北京 101111
Quick Overview for MEPE 抗体 (AA 201-300) (AbBy Fluor® 488) (ABIN1400188)
抗原
See all MEPE 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 201-300
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交叉反应
- 小鼠
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预测反应
- Human
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human MEPE
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亚型
- IgG
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anti-Matrix Extracellular phosphoglycoprotein (MEPE) (AA 28-224) antibody
MEPE 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Matrix Extracellular phosphoglycoprotein (MEPE) (AA 212-445) antibodyMEPE 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Matrix Extracellular phosphoglycoprotein (MEPE) (AA 350-399) antibodyMEPE 适用: 人, 犬, 豚鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- MEPE (Matrix Extracellular phosphoglycoprotein (MEPE))
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别名
- MEPE
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背景
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Synonyms: Matrix extracellular phosphoglycoprotein, MEPE, MEPE_HUMAN, OF45, Osteoblast/osteocyte factor 45.
Background: MEPE is a 525 amino acid extracellular matrix protein. Expressed in osteocytes and brain, MEPE is a regulator of bone metabolism that is thought to mediate mineralization and demineralization within the osteocyte microenvironment. MEPE contains an RGD cell-attachment motif and shares molecular similarities with several dentin-bone extracellular matrix RGD-containing phosphoglycoproteins, including OPN (osteopontin) and DSP (dentin sialophosphoprotein). Via its ability to control bone mineralization, MEPE is associated with various developmental events such as skeletogenesis, bone regeneration and odontogenesis. MEPE is secreted in hypophosphatemic osteomalacia tumors, suggesting a possible role in the pathophysiology of bone-related cancers.
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基因ID
- 56955
抗原
-
