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ERN1 抗体 (AA 252-260) (FITC)

Cited in 1 publication. This FITC-conjugated 兔 多克隆 anti-ERN1 antibody specifically detects ERN1 in WB, FACS, IF (cc) 和 IF (p). The antibody is reactive with 人, 小鼠, 大鼠 和 Pig samples.
产品编号 ABIN1400144
发货至: 中国
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Quick Overview for ERN1 抗体 (AA 252-260) (FITC) (ABIN1400144)

抗原

See all ERN1 抗体
ERN1 (Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1))

适用

  • 81
  • 60
  • 53
  • 15
  • 1
  • 1
人, 小鼠, 大鼠, Pig

宿主

  • 82
  • 4
  • 3
  • 1

克隆类型

  • 72
  • 18
多克隆

标记

  • 38
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  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
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This ERN1 antibody is conjugated to FITC

应用范围

  • 85
  • 49
  • 31
  • 25
  • 25
  • 20
  • 20
  • 18
  • 9
  • 6
  • 5
  • 3
  • 2
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Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 16
    • 15
    • 7
    • 6
    • 6
    • 5
    • 5
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    • 1
    AA 252-260

    交叉反应

    人, 小鼠, Pig, 大鼠

    预测反应

    Dog,Cow,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human IRE1a

    亚型

    IgG
  • 应用备注

    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • Li, Han, Shi: "IRE1?-XBP1 Pathway Is Activated Upon Induction of Single-Prolonged Stress in Rat Neurons of the Medial Prefrontal Cortex." in: Journal of molecular neuroscience : MN, (2015) (PubMed).

  • 抗原

    ERN1 (Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1))

    别名

    IRE1a

    背景

    Synonyms: IRE1, IRE1P, IRE1a, hIRE1p, Serine/threonine-protein kinase/endoribonuclease IRE1, Endoplasmic reticulum-to-nucleus signaling 1, Inositol-requiring protein 1, Ire1-alpha, ERN1

    Background: Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.

    基因ID

    2081

    UniProt

    O75460

    途径

    ER-Nucleus Signaling, Unfolded Protein Response
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